35 citations
,
March 2011 in “International Journal of Dermatology” This study concluded that patients with metabolic syndrome, regardless of androgenetic alopecia presence, were more insulin resistant than those with only androgenetic alopecia or healthy controls, indicating no true association between alopecia and insulin resistance.
69 citations
,
April 2010 in “British Journal of Dermatology” This study found a significant association between androgenetic alopecia and metabolic syndrome, highlighting high-density lipoprotein cholesterol as a particularly important factor.
21 citations
,
October 2009 in “Dermatology” This study found that male pattern hair loss may be associated with differences in serum levels of androstenedione, cortisol, 17 beta-estradiol, and luteinizing hormone, compared to controls.
28 citations
,
March 2009 in “Clinical and Experimental Dermatology” This article discusses the potential relationship between androgenic alopecia and insulin resistance but presents no new clinical findings, calling for further research on the topic.
210 citations
,
February 2008 in “Nature genetics” This study found mutations in the P2RY5 gene that are linked to autosomal recessive woolly hair in Pakistani families, implicating it in hair texture determination.
52 citations
,
April 2004 in “Journal of The American Academy of Dermatology” This article proposes three mechanisms by which dihydrotestosterone may contribute to baldness but reports no new research findings.
29 citations
,
February 2004 in “Experimental and Clinical Endocrinology & Diabetes” This study suggests that many men with premature balding exhibit a hormonal pattern similar to some aspects of polycystic ovary syndrome in women.
77 citations
,
March 2001 in “Clinics in Dermatology” This article discusses treatment approaches for female pattern hair loss and concludes that available medical treatments are effective in reversing or stabilizing the condition in most cases of mild-to-moderate severity.
28 citations
,
June 2000 in “PubMed” This article reviews the molecular mechanisms involved in androgenetic alopecia, focusing on the role of type 2 5α-reductase and DHT, but presents no new findings.
4 citations
,
January 2000 in “PubMed” In this study, researchers found that young men with premature androgenetic alopecia had a hormonal profile similar to the pattern seen in women with polycystic ovary syndrome, suggesting a possible genetic link.
52 citations
,
March 1987 in “Journal of the American Academy of Dermatology” This study found that men with rapidly progressive male pattern baldness had elevated serum dehydroepiandrosterone sulfate levels, suggesting that adrenal hyperactivity may contribute to alopecia in genetically susceptible young men.
