Pathogenesis of Androgenetic Alopecia
April 2004
in “
Journal of The American Academy of Dermatology
”
TLDR Male pattern baldness involves three mechanisms and finasteride can help reverse it.
This 2004 scientific paper discusses the pathogenesis of androgenetic alopecia (AGA), also known as male pattern baldness. The paper proposes three mechanisms that contribute to AGA and suggests that further research is needed to fully understand the condition. The paper also introduces the concept of "kenogen," a resting phase of the hair follicle that may be a key factor in the development of AGA. The paper concludes that finasteride, a 5 alpha-reductase inhibitor, has been shown to reverse hair miniaturization in men with AGA.