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GlossaryDehydroepiandrosterone Sulfate

hormone precursor influencing sex hormones and hair growth

Dehydroepiandrosterone Sulfate (DHEA-S) is a hormone produced primarily by the adrenal glands, and it serves as a precursor to male and female sex hormones, including testosterone and estrogen. It plays a role in the development of secondary sexual characteristics and can influence hair growth and skin health. Elevated or decreased levels of DHEA-S can be indicative of various health conditions, such as adrenal disorders or polycystic ovary syndrome (PCOS).

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Elevated Dehydroepiandrosterone Sulfate Levels as the Reproductive Phenotype in the Brothers of Women with Polycystic Ovary Syndrome

research Elevated Dehydroepiandrosterone Sulfate Levels as the Reproductive Phenotype in the Brothers of Women with Polycystic Ovary Syndrome

27 citations, May 2002 in “The Journal of Clinical Endocrinology & Metabolism”

Brothers of women with PCOS tend to have higher levels of a hormone called DHEAS, indicating a possible genetic link.

Treatment of Androgenic Disorders with Dexamethasone: Dose-Response Relationship for Suppression of Dehydroepiandrosterone Sulfate

research Treatment of Androgenic Disorders with Dexamethasone: Dose-Response Relationship for Suppression of Dehydroepiandrosterone Sulfate

18 citations, January 1990 in “Journal of The American Academy of Dermatology”

Lower doses of dexamethasone can safely reduce high DHEAS levels in women with androgenic disorders.

research Hyposecretion of the Adrenal Androgen Dehydroepiandrosterone Sulfate (DHEA-S) in the Majority of Alopecia Areata Patients: Is It a Primitive and Pathogenic Perturbation of the Hypothalamic-Pituitary-Adrenal Axis?

3 citations, January 2011 in “International journal of trichology”

Low DHEA-S levels might be linked to alopecia areata and could be a potential treatment target.

research Evaluating Testosterone and Dehydroepiandrosterone Sulfate as Biomarkers for Male Androgenetic Alopecia

February 2025 in “East African Scholars Journal of Medical Sciences”

Higher testosterone and DHEA-S levels may be linked to male pattern baldness.

A Unique Case of Isolated Dehydroepiandrosterone-Sulfate Secreting Adrenocortical Carcinoma: A Case Report with Review of the Literature

research A Unique Case of Isolated Dehydroepiandrosterone-Sulfate Secreting Adrenocortical Carcinoma: A Case Report with Review of the Literature

October 2021 in “Acta Scientific Medical Sciences”

A woman was diagnosed with a rare adrenal gland cancer that did not show usual hormone-related symptoms.

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community Cardio for more than 60 minutes reduces DHT levels and improve hair growth

in Research/Science 126 upvotes 1 month ago

Long aerobic exercise (over 60 minutes) can reduce DHT levels and improve hair health. Some users discuss using Tadalafil (Cialis) to further reduce DHT after exercise, while others mention using treatments like Minoxidil, Finasteride, and RU58841 for hair growth.

community 16 months finasteride progress but slowly losing hair again

in Progress Pictures 137 upvotes 1 month ago

A 21-year-old male experienced initial success with finasteride for 16 months but is now losing hair again. He is considering switching to dutasteride and adding oral minoxidil, while also investigating environmental and health factors.

community Please take a vitamin & hormone test

in Chat 254 upvotes 3 months ago

Checking vitamin and hormone levels is important for addressing hair loss, as deficiencies in vitamin D, zinc, and iron can affect hair growth. Treatments like finasteride, minoxidil, and vitamin supplements are used, but addressing deficiencies is crucial for effectiveness.

community here is why isotretinoin might cause hair loss and maybe why dupa happens.

in Research/Science 7 upvotes 1 year ago

Isotretinoin may cause hair loss by increasing DHT through a precursor androgen, DHEAS. Treatments like topical antiandrogens (RU58841, pyrilutamide) and drugs increasing PPAR-y expression (pioglitazone) might prevent this hair loss.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 4 months ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.