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    Glossary Dehydroepiandrosterone Sulfate

    hormone precursor influencing sex hormones and hair growth

    Dehydroepiandrosterone Sulfate (DHEA-S) is a hormone produced primarily by the adrenal glands, and it serves as a precursor to male and female sex hormones, including testosterone and estrogen. It plays a role in the development of secondary sexual characteristics and can influence hair growth and skin health. Elevated or decreased levels of DHEA-S can be indicative of various health conditions, such as adrenal disorders or polycystic ovary syndrome (PCOS).

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    1. Puberty in Boys: Correlation of Plasma Levels of Gonadotropins (LH, FSH), Androgens (Testosterone, Androstenedione, Dehydroepiandrosterone and Its Sulfate), Estrogens (Estrone and Estradiol) and Progestins (Progesterone and 17-Hydroxyprogesterone) The Journal of Clinical Endocrinology & Metabolism · 1975 · 96 citations
    2. Serum elevation of dehydroepiandrosterone sulfate associated with male pattern baldness in young men Journal of the American Academy of Dermatology · 1987 · 52 citations
    3. Elevated Dehydroepiandrosterone Sulfate Levels as the Reproductive Phenotype in the Brothers of Women with Polycystic Ovary Syndrome The Journal of Clinical Endocrinology & Metabolism · 2002 · 27 citations
    4. Treatment of androgenic disorders with dexamethasone: Dose-response relationship for suppression of dehydroepiandrosterone sulfate Journal of The American Academy of Dermatology · 1990 · 18 citations
    5. Role of Dehydroepiandrosterone and Dehydroepiandrosterone Sulfate for the Maintenance of Axillary Hair in Women Hormone and Metabolic Research · 1993 · 5 citations
    6. Hyposecretion of the adrenal androgen dehydroepiandrosterone sulfate (DHEA-S) in the majority of the alopecia areata patients: Is it a primitive and pathogenic perturbation of hypothalamic-pituitary-adrenal axis? International journal of trichology · 2011 · 3 citations
    7. An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of dehydroepiandrosterone sulfate in human serum and plasma Clinical Chemistry and Laboratory Medicine (CCLM) · 2025 · 1 citations
    8. Association of childhood dehydroepiandrosterone sulfate concentration, pubertal development, and DNA methylation at puberty-related genes European Journal of Endocrinology · 2024 · 1 citations
    9. Evaluating Testosterone and Dehydroepiandrosterone Sulfate (DHEA-S) as Biomarkers for Male Androgenetic Alopecia East African Scholars Journal of Medical Sciences · 2025
    10. Sex-Specific Total Testosterone and Dehydroepiandrosterone Sulfate Status in Noncritically Ill Hospitalized Patients with Coronavirus Disease 2019: A Cross-Sectional Study. PubMed · 2023
    11. Comparison of efficacy of diode laser in patients of facial hirsutism with normal dehydroepiandrosterone sulfate and dihydrotestosterone versus deranged dehydroepiandrosterone sulfate and dihydrotestosterone level—A longitudinal study Dermatologic Therapy · 2022
    12. A Unique Case of Isolated Dehydroepiandrosterone-Sulfate Secreting Adrenocortical Carcinoma: A Case Report with Review of the Literature Acta Scientific Medical Sciences · 2021
    13. Dehydroepiandrosterone Sulfate Level is Lower in Polycystic Ovary Syndrome Patients with Autoimmune Thyroid Disease Turkiye Klinikleri Journal of Endocrinology · 2015
    14. 유전성 안드로겐탈모증 여성환자의 임상양상과 혈중 dehydroepiandrosterone sulfate 및 total testosterone 치 대한피부과학회지 · 2001
    15. Serum levels of testosterone and dehydroepiandrosterone sulfate in females with acne and/or female pattern hair loss Journal of Skin and Sexually Transmitted Diseases · 2020
    16. SERUM-CONCENTRATIONS OF Dehydroepyandrosterone-sulfate IN MEN WITH ANDROGENETIC ALOPECIA DOAJ (DOAJ: Directory of Open Access Journals) · 2004
    17. SERUM-CONCENTRATIONS OF Dehydroepyandrosterone-sulfate IN MEN WITH ANDROGENETIC ALOPECIA Journal of IMAB · 2012
    18. [Effects of dehydroepiandrosterone-sulfate on hair growth in mice and guinea pigs]. PubMed · 1972 · 1 citations
    19. Hyperandrogenism Due to a Testosterone-Secreting Sertoli-Leydig Cell Tumor Associated With a Dehydroepiandrosterone Sulfate-Secreting Adrenal Adenoma in a Postmenopausal Woman: Case Presentation and Review of Literature Endocrine Practice · 2009 · 9 citations
    20. Steroid Sulfatase in the Human Hair Follicle Concentrates in the Dermal Papilla Journal of Investigative Dermatology · 2001 · 61 citations
    21. Roles of steroid sulfatase in brain and other tissues Physiological Research · 2008 · 22 citations
    22. SERUM-CONCENTRATIONS OF DEHYDROEPYAN- DROSTERONE-SULFATE IN MEN WITH ANDROGE- NETIC ALOPECIA DOAJ (DOAJ: Directory of Open Access Journals) · 2004
    23. Endocrine and Intracrine Sources of Androgens in Women: Inhibition of Breast Cancer and Other Roles of Androgens and Their Precursor Dehydroepiandrosterone Endocrine Reviews · 2003 · 515 citations
    24. Anti-SARS-CoV-2 Action of 5α-Reductase Inhibitors May Be Mediated by Dehydroepiandrosterone. Letter. The Journal of Urology · 2022 · 1 citations
    25. Sulfation of minoxidil by human liver phenol sulfotransferase Biochemical Pharmacology · 1990 · 68 citations
    26. A Prospective Study of the Prevalence of the Polycystic Ovary Syndrome in Unselected Caucasian Women from Spain1 The Journal of Clinical Endocrinology and Metabolism · 2000 · 491 citations
    27. A Prospective Study of the Prevalence of the Polycystic Ovary Syndrome in Unselected Caucasian Women from Spain The Journal of Clinical Endocrinology and Metabolism · 2000 · 298 citations
    28. The Rise in Adrenal Androgen Biosynthesis: Adrenarche Seminars in Reproductive Medicine · 2004 · 173 citations
    29. The effects of two doses of spironolactone on serum androgens and anagen hair in hirsute women Fertility and sterility · 1985 · 142 citations
    30. LC‐MS/MS‐based method for long‐term steroid profiling in human scalp hair Clinical Endocrinology · 2015 · 134 citations