Hormonal Profile in Men With Premature Androgenic Alopecia

The study conducted 23 years ago involved 15 young men with premature androgenetic alopecia, a condition that can cause serious psychological trauma and financial burden due to treatments. The hormonal analysis of these men revealed a significantly lower plasma level of sexual binding globulin (SHBG) and FSH, and a nearly significantly higher concentration of 17 alpha-hydroxyprogesterone. These hormonal patterns were similar to those found in women suffering from polycystic ovaries syndrome (PCOS). The study suggested that premature balding could be a male hormonal equivalent of PCOS, aligning with previous genetic studies that indicated a common genetic basis in families where balding and excessive hair growth were frequent in male members.