Is There Really a Relationship Between Androgenetic Alopecia and Metabolic Syndrome?

November 2015 in “ Dermatology Research and Practice ”

Seyran Ozbas Gok, Asli Akin Belli, Emine Dervis

androgenetic alopecia metabolic syndrome systolic blood pressure fasting blood glucose waist circumference AGA MS

TLDR No clear link between hair loss and metabolic syndrome, but some differences in blood pressure and glucose levels.

This study investigated the relationship between androgenetic alopecia (AGA) and metabolic syndrome (MS) in 74 male AGA patients and 42 controls. The study found no significant difference in the rate of MS between AGA and control groups. However, AGA patients had significantly high systolic blood pressure levels, while control group had significantly high fasting blood glucose and waist circumference levels. The study suggests that the pathophysiological connection between AGA and MS has not been completely elucidated.

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Research cited in this study

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research Alopecia and Its Association with Coronary Heart Disease and Cardiovascular Risk Factors: A Meta-Analysis

48 citations, October 2014 in “International Journal of Cardiology”

People with alopecia are at higher risk for heart disease and have more heart-related risk factors.

Higher Body Mass Index Is Associated With Greater Severity of Alopecia in Men With Male-Pattern Androgenetic Alopecia in Taiwan: A Cross-Sectional Study

research Higher Body Mass Index Is Associated With Greater Severity of Alopecia in Men With Male-Pattern Androgenetic Alopecia in Taiwan: A Cross-Sectional Study

38 citations, November 2013 in “Journal of The American Academy of Dermatology”

Higher BMI links to worse hair loss in Taiwanese men.

research The Investigation of Insulin Resistance and Metabolic Syndrome in Male Patients with Early-Onset Androgenetic Alopecia

42 citations, April 2011 in “European Journal of Dermatology”

Early balding men may have insulin resistance, but lifestyle changes can help.

research Androgenetic Alopecia and Insulin Resistance: Are They Truly Associated?

35 citations, April 2011 in “International Journal of Dermatology”

No true link between AGA and insulin resistance, but coexistence may worsen AGA.

research The Association of Insulin Resistance and Metabolic Syndrome in Early Androgenetic Alopecia

18 citations, December 2010 in “PubMed”

People with early hair loss may have higher insulin levels and a greater chance of developing metabolic syndrome.

research Hypertension and Aldosterone Levels in Women with Early-Onset Androgenetic Alopecia

45 citations, November 2009 in “British Journal of Dermatology”

Women with early hair loss have higher blood pressure and aldosterone; screening and treatment may help.

research Androgenic Alopecia and Insulin Resistance: Are They Really Related?

28 citations, March 2009 in “Clinical and Experimental Dermatology”

There is no significant link between male pattern baldness and insulin resistance.

research Association of Androgenetic Alopecia and Hypertension

34 citations, May 2007 in “PubMed”

Balding in men is strongly linked to high blood pressure and family history.

research Established Risk Factors for Coronary Heart Disease Are Unrelated to Androgen-Induced Baldness in Female-to-Male Transsexuals

57 citations, January 2004 in “Journal of Endocrinology”

Baldness caused by male hormones in female-to-male transsexuals doesn't increase the risk of heart disease.

research Hair Loss, Insulin Resistance, and Heredity in Middle-Aged Women: A Population-Based Study

49 citations, June 2003 in “European journal of cardiovascular prevention & rehabilitation”

Hair loss in middle-aged women is often linked to insulin resistance and a family history of hair loss, particularly from their fathers.

research Female Pattern Hair Loss

226 citations, September 2001 in “Journal of The American Academy of Dermatology”

Hair loss in women is genetic, diagnosed by examination and biopsy, and treated with minoxidil, finasteride, or transplantation.

research Early Androgenetic Alopecia as a Marker of Insulin Resistance

115 citations, September 2000 in “The Lancet”

Early hair loss may indicate risk of insulin resistance.

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 5 months ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Do we have to be junkies? That's funny

in Research/Science 14 upvotes 9 months ago

The conversation discusses using finasteride, dutasteride, minoxidil, cialis, and metformin to protect hair and health. Some users caution against self-prescribing these drugs due to potential risks and complications.

community How much do you guys think diet and sleep affects results?

in Research/Science 36 upvotes 1 year ago

The conversation discusses whether lifestyle factors like diet and sleep affect hair growth in people with reversible hair loss. Some believe these factors, along with treatments like minoxidil, finasteride, and RU58841, can improve hair health, while others argue hair loss is mostly determined by genetics and DHT sensitivity.

community Dutasteride Infertility Debunked: Low T causes true infertility.

in Finasteride/Dutasteride 162 upvotes 1 week ago

Dutasteride and finasteride may temporarily affect semen quality but are unlikely to cause permanent infertility. The Kim et al. study is criticized for poor methodology, and many prefer hair retention over potential fertility concerns, using treatments like dutasteride, finasteride, and minoxidil.

community Update on my progress after 10,5 months

in Progress Pictures 146 upvotes 2 months ago

The user has been using a combination of oral finasteride, oral dutasteride, topical and oral minoxidil, microneedling, and keto shampoo for hair loss, experiencing significant shedding recently. Suggestions include simplifying the regimen by dropping finasteride and topical minoxidil, and possibly adding RU58841, while others advise maintaining the current approach for consistent results.

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in Chat 262 upvotes 6 months ago

Many younger men are experiencing hair loss due to genetics, diet, stress, and lifestyle changes. Treatments like finasteride and minoxidil are mentioned, with some users noting improvements.

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