TLDR Androgenetic alopecia is linked to higher cardiovascular and metabolic risks, possibly due to irisin resistance.
This study examines the relationship between androgenetic alopecia (AGA), metabolic syndrome (MetS), and cardiovascular risks, focusing on the role of irisin, a hormone linked to energy metabolism. Conducted on 44 AGA patients and 22 healthy controls, the research found that AGA is associated with increased cardiovascular and metabolic risks, including higher BMI, hypertension, and dyslipidemia. AGA patients had significantly higher serum irisin levels, which correlated positively with BMI and carotid intima-media thickness (CIMT), suggesting irisin resistance and a potential link to cardiovascular risk. The study suggests that irisin levels could serve as a predictor for MetS and cardiovascular risks in AGA patients, highlighting the potential of irisin as a biomarker for these comorbidities. However, further research is needed to fully understand its role and receptor interactions.
1 citations,
January 2017 in “International Journal of Research in Medical Sciences” Men with severe hair loss are more likely to have metabolic syndrome, a condition linked to heart disease.
1 citations,
January 2017 in “Springer eBooks” The document explains how hair loss patterns in men and women, known as Androgenetic alopecia, are classified using the Hamilton-Norwood system for men and the Ludwig grade system for women.
48 citations,
October 2014 in “International Journal of Cardiology” People with alopecia are at higher risk for heart disease and have more heart-related risk factors.
14 citations,
March 2014 in “Journal of The European Academy of Dermatology and Venereology” Young adults with hair loss face higher risk of stiff arteries.
110 citations,
July 2010 in “Journal of The American Academy of Dermatology” Hair loss linked to higher heart disease risk in both men and women.
69 citations,
April 2010 in “British Journal of Dermatology” Balding men, especially young ones, may have higher risk of heart issues and diabetes; check cholesterol levels.
77 citations,
March 2001 in “Clinics in Dermatology” Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.
February 2024 in “Heliyon” People with androgenetic alopecia have different lipid levels in their blood, which vary between men and women, and may be linked to a higher risk of metabolic syndrome.
14 citations,
January 2018 in “Advances in Clinical Chemistry” The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.
11 citations,
January 2020 in “Medical Journal Armed Forces India” Insulin resistance is a complex condition that can lead to many diseases and has few treatment options.
January 2024 in “International Journal of Dermatology Venereology and Leprosy Sciences” Patients with acne vulgaris have lower serum irisin levels.
1 citations,
May 2022 in “IntechOpen eBooks” Obesity leads to physical, metabolic, reproductive issues, higher healthcare costs, and mental health problems.
