TLDR Patients with acne vulgaris have lower serum irisin levels.
The study investigates the serum irisin levels in patients with acne vulgaris, a common inflammatory skin condition affecting hair follicles and sebaceous glands. Acne vulgaris is characterized by comedones and inflammatory lesions on the face, chest, shoulders, and back. Insulin resistance, which decreases cell sensitivity to insulin, is linked to various skin conditions, including acne vulgaris. Irisin, a hormone associated with body size, shape, and obesity, can improve insulin resistance by stimulating thermogenesis and energy consumption in subcutaneous adipose tissue. The intervention in the study led to decreased glucose and insulin levels, indicating improved insulin resistance.
8 citations,
September 2018 in “Journal of Cosmetic Dermatology” Lower irisin levels in the blood may indicate more severe acne.
71 citations,
November 2013 in “Clinics in Dermatology” Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.
22 citations,
August 2013 in “International journal of gynaecology and obstetrics” Acne severity in women with PCOS is linked to younger age, lower body weight, and more body hair, but not to hormone levels.
39 citations,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.
99 citations,
December 2010 in “Journal of The European Academy of Dermatology and Venereology” The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.
November 2020 in “ALEXMED ePosters (Online)” People with PCOS often have skin problems like excessive hair growth, hair loss, acne, and dark patches, which are linked to hormonal and metabolic imbalances.
1 citations,
March 2020 in “International journal of reproduction, contraception, obstetrics and gynecology” The study concluded that the most common skin problems in women with PCOS are excess hair, acne, oily skin, hair loss, dark skin patches, and skin tags.
January 2020 in “Open Journal of Obstetrics and Gynecology” All women with Polycystic Ovary Syndrome (PCOS) in a study had at least one skin disorder, with the most common being excessive hair growth, acne, dark skin patches, hair loss, and oily skin.
28 citations,
January 2017 in “Indian Dermatology Online Journal” Skin problems like acne, excessive hair growth, and oily skin are common in women with PCOS and can help with early diagnosis.
