Acne-Associated Syndromes: Models for Better Understanding of Acne Pathogenesis

December 2010 in “ Journal of The European Academy of Dermatology and Venereology ”

W Chen, B. Obermayer-Pietsch, Jin-Bon Hong, Melnik Bc, Osamu Yamada, Clio Dessinioti, Ju Q, Liakou Ai, Safaa Al-Khuzaei, Andreas Katsambas, Johannes Ring, Zouboulis Cc

acne Apert syndrome FGFR2 gene FoxO1 androgen-dependent up-regulation FGF synthesis isotretinoin insulinotropic foods Accutane

Studysummary This article discusses the association of acne with various systemic diseases, emphasizing the role of androgen steroids, insulin resistance, and inflammation in acne pathogenesis, but it reports no new clinical results.

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