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GlossaryIsotretinoin

oral medication for severe acne unresponsive to other treatments

Isotretinoin, also known by brand names like Accutane, is a powerful oral medication primarily used to treat severe acne that hasn't responded to other treatments. It works by reducing the amount of oil released by oil glands in your skin, helping your skin renew itself more quickly. While highly effective, it can have significant side effects and is typically prescribed under strict medical supervision.

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research Action of Isotretinoin in Acne Rosacea and Gram-Negative Folliculitis

175 citations, April 1982 in “Journal of The American Academy of Dermatology”

Isotretinoin is highly effective in treating severe acne, rosacea, and gram-negative folliculitis.

research Isotretinoin Treatment of Acne and Related Disorders: An Update

126 citations, October 1983 in “Journal of The American Academy of Dermatology”

Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.

research Adverse Effects of Isotretinoin: A Retrospective Review of 1743 Patients

121 citations, June 2010 in “Australasian Journal of Dermatology”

Most people on isotretinoin had chapped lips, but only a few stopped the medicine due to side effects.

research Apoptosis May Explain the Pharmacological Mode of Action and Adverse Effects of Isotretinoin, Including Teratogenicity

66 citations, January 2017 in “Acta dermato-venereologica”

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

research Oral Isotretinoin for Acne

58 citations, November 2018 in “Cochrane library”

Oral isotretinoin may slightly improve acne but increases the risk of side effects like dry lips and skin; more research is needed to understand its full risks and benefits.

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community Isotretinoin and Tretinoin difference

in Product 2 upvotes 1 month ago

Isotretinoin and tretinoin are different; isotretinoin can cause hair loss and has more side effects. Tretinoin may affect minoxidil absorption, and users suggest waiting before applying minoxidil.

community here is why isotretinoin might cause hair loss and maybe why dupa happens.

in Research/Science 7 upvotes 1 year ago

Isotretinoin may cause hair loss by increasing DHT through a precursor androgen, DHEAS. Treatments like topical antiandrogens (RU58841, pyrilutamide) and drugs increasing PPAR-y expression (pioglitazone) might prevent this hair loss.

community Oral min and Isotretinoin (accutane) to respond

in Chat 4 months ago

Oral minoxidil combined with isotretinoin may improve hair loss treatment effectiveness. Tretinoin is known to increase the absorption of topical minoxidil.

community Which retinoid for better min absorption?

in Product 4 upvotes 3 months ago

User is on vacation in Greece and wants to buy tretinoin or isotretinoin to improve Minoxidil absorption. They are considering isotretinoin since it is available over-the-counter in Greece but requires a prescription back home.

community Dut/Minox/Needling to Dut/Oral Minox/Tretinoin/Needling

in Minoxidil 3 upvotes 7 months ago

The user had been using Minoxidil and Dutasteride with micro-needling but experienced hair loss after switching Minoxidil brands. Their doctor prescribed oral Minoxidil and Tretinoin, but the pharmacist suggested isotretinoin might be a more cost-effective alternative.

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