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    Glossary Isotretinoin

    oral medication for severe acne unresponsive to other treatments

    Isotretinoin, also known by brand names like Accutane, is a powerful oral medication primarily used to treat severe acne that hasn't responded to other treatments. It works by reducing the amount of oil released by oil glands in your skin, helping your skin renew itself more quickly. While highly effective, it can have significant side effects and is typically prescribed under strict medical supervision.

    Research 10 of 1000+

    1. Action of isotretinoin in acne rosacea and gram-negative folliculitis Journal of The American Academy of Dermatology · 1982 · 175 citations
    2. Isotretinoin treatment of acne and related disorders: An update Journal of The American Academy of Dermatology · 1983 · 126 citations
    3. Adverse effects of isotretinoin: A retrospective review of 1743 patients started on isotretinoin Australasian Journal of Dermatology · 2010 · 121 citations
    4. Advice on the safe introduction and continued use of isotretinoin in acne in the U.K. 2010 British Journal of Dermatology · 2010 · 98 citations
    5. Apoptosis May Explain the Pharmacological Mode of Action and Adverse Effects of Isotretinoin, Including Teratogenicity Acta dermato-venereologica · 2017 · 66 citations
    6. Oral isotretinoin for acne Cochrane library · 2018 · 58 citations
    7. Enduring sexual dysfunction after treatment with antidepressants, 5α-reductase inhibitors and isotretinoin: 300 cases International journal of risk & safety in medicine · 2018 · 54 citations
    8. Actions of isotretinoin and etretinate on the pilosebaceous unit Journal of the American Academy of Dermatology · 1982 · 46 citations
    9. Trypanocidal Effect of Isotretinoin through the Inhibition of Polyamine and Amino Acid Transporters in Trypanosoma cruzi PLoS neglected tropical diseases · 2017 · 41 citations
    10. Avaliação dos efeitos adversos clínicos e alterações laboratoriais em pacientes com acne vulgar tratados com isotretinoína oral Anais Brasileiros de Dermatologia · 2010 · 41 citations
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    Community 10 of 30

    1. Does anyone here take isotretinoin to make their scalp less oily? Reddit · 9 Apr 2026
    2. Isotretinoin and Tretinoin difference Reddit · 9 Nov 2024
    3. here is why isotretinoin might cause hair loss and maybe why dupa happens. Reddit · 30 Jun 2023
    4. Is there anyone out there who can help me? Reddit · 16 Sept 2026
    5. Effect of Accutane(acne medication) on hair? Reddit · 8 Sept 2026
    6. How to deal with overproduction of sebum? Reddit · 17 Aug 2026
    7. 6 Months of Dutasteride and Min Reddit · 8 Jul 2026
    8. DHT Itch and Oily Scalp Explained (and how to fix it) Reddit · 4 Jun 2026
    9. Michael Scott Season 1 vs Season 7 Hair Reddit · 21 Apr 2026
    10. When you think about it blocking dht is not that big of a deal as it’s made out to be Reddit · 23 Feb 2026
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