Does Pyrilutamide lowers sebum production?
    11/22/2025

    From the encyclopedia
    Pyrilutamide →

    Experimental topical anti-androgen, also known as KX-826

    Dutasteride →

    5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride

    Ketoconazole →

    Antifungal, best known as a dandruff shampoo

    At a glance
    In this question or advice post, the primary subjects mentioned are
    💊 Dutasteride (oral) 0.5 mg daily 3 weeks
    💧 Ketoconazole (topical) 2%
    💧 Selsun Blue (topical)
    💧 MCT Oil (topical)
    the tone is 😐 neutral.

    Other terms

    Pyrilutamide's effect on sebum production and scalp inflammation is unclear, with users noting no significant changes. Isotretinoin is mentioned as effective for reducing sebum, while Dutasteride and various shampoos have limited impact on oiliness and seborrheic dermatitis.
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