Topical Solutions for Androgenetic Alopecia: Evaluating Efficacy and Safety

    July 2024 in “ Forum Dermatologicum
    Mateusz Michał Koralewicz, Olga Agnieszka Szatkowska
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    TLDR Topical treatments for hair loss can be effective but need careful safety evaluation.
    This review examines the efficacy and safety of various topical treatments for androgenetic alopecia (AGA), highlighting their potential to minimize systemic side effects compared to oral medications. The article covers the pharmacology, mechanisms of action, clinical efficacy, and adverse events of topical agents such as minoxidil, finasteride, ketoconazole shampoo, clascoterone, latanoprost, spironolactone, flutamide, cetirizine, pyrilutamide, and GT20029. The findings suggest that while these topical solutions can be effective, their safety profiles and practical considerations must be carefully evaluated to optimize patient outcomes.
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