Nudging Hair Shedding by Antidandruff Shampoos: A Comparison of 1% Ketoconazole, 1% Piroctone Olamine, and 1% Zinc Pyrithione Formulations

    October 2002 in “ International Journal of Cosmetic Science ”
    Piérard-Franchimont C, Véronique Goffin, Frédérique Henry, Isabelle Uhoda, C. Braham, Gérald Pierard
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    TLDR All three shampoos reduced dandruff and hair loss, but ketoconazole and piroctone olamine also made hair thicker.
    In a 2002 study involving 150 men with telogen effluvium related to androgenic alopecia and dandruff, the efficacy of three antidandruff shampoos with 1% concentrations of ketoconazole (KTZ), piroctone olamine (PTO), and zinc pyrithione (ZPT) was evaluated. The men were divided into three groups of 50 and used their assigned shampoo 2-3 times a week for 6 months. The study concluded that all shampoos were effective in reducing pruritus, dandruff, and hair shedding, with KTZ and PTO also increasing hair shaft diameter and slightly decreasing sebum output, unlike ZPT. This suggests that while all three shampoos can control telogen effluvium, KTZ and PTO may offer additional benefits in improving hair shaft thickness.
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      in Ketoconazole  11 upvotes 1 year ago
      The user has been using finasteride and ketoconazole for hair loss and is considering changing shampoos due to dryness caused by ketoconazole. Responses suggest that stopping ketoconazole won't affect hair loss unless the user has seborrheic dermatitis, and recommend using conditioner or using ketoconazole shampoo less frequently.

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      in Chat  6 upvotes 1 year ago
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      in Treatment  7 upvotes 1 year ago
      OP struggles with scalp flakes causing hair loss and has tried Selsun Blue, Ketoconazole, and ZPT Shampoo without success. Suggestions include using salicylic acid shampoo, shaving the head, using Nizoral, and combining treatments like Minoxidil and finasteride.

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      in Transplants  81 upvotes 2 years ago
      The conversation is about the effectiveness of finasteride (fin) in preventing hair loss after a hair transplant. Some users have experienced hair thinning and loss after stopping finasteride, while others have had success with finasteride and minoxidil (min) in maintaining their transplanted hair. The general consensus is that finasteride is important for younger patients to prevent further hair loss.

      community Shoutout to Zinc pyrithione and Piroctone olamine

      in Product  3 upvotes 10 months ago
      Zinc pyrithione and piroctone olamine are effective for reducing hair shedding, possibly more so than ketoconazole. There is a concern about zinc pyrithione shampoo interfering with minoxidil, but it's unclear if this is proven.

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