Improvement in the Inflammatory Aspect of Androgenetic Alopecia: A Pilot Study with an Antimicrobial Lotion

January 1996 in “ Journal of Dermatological Treatment ”

Gérald Pierard, Claudine Piérard-Franchimont, Nazli Nikkels-Tassoudji, Arjen Nikkels, D. Saint Leger

androgenetic alopecia antimicrobial lotion piroctone olamine triclosan hair density inflammation microorganisms infrainfundibulum AGA

TLDR Antimicrobial lotion reduces inflammation and increases hair density in hair loss patients.

A pilot study with varying sample sizes found that applying an antimicrobial lotion containing piroctone olamine and triclosan twice daily for 3-18 months significantly reduced inflammation and increased hair density in individuals with androgenetic alopecia. The lotion was well-tolerated with no adverse effects reported, suggesting that it may be a promising treatment option for AGA. However, larger studies are needed to confirm these findings. The study suggests that controlling microorganisms in the infrainfundibulum could potentially prevent and partially reverse hair loss in AGA.

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Research cited in this study

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research Expression of the L-Fucose Moiety on Infrainfundibular Follicular Keratinocytes of Terminal Follicles, Its Decreased Expression on Vellus and Indeterminate Follicles of Androgenetic Alopecia, and Re-Expression in Drug-Induced Hair Regrowth

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