Natural History of Androgenetic Alopecia

January 1990 in “ Clinical and Experimental Dermatology ”

Elise A. Olsen, T.A. Buller, Steve Weiner, Elizabeth R. DeLong

androgenetic alopecia hair count topical minoxidil hair growth Rogaine

Studysummary This study observed that without any treatment, hair counts did not increase, suggesting that counting methods are unlikely to explain the 'placebo-effect' seen in previous minoxidil studies. Our plain-language summary of this paper — not a Tressless recommendation.

The natural progression of androgenetic alopecia was observed in several studies over a 10-month period. The studies found a gradual decrease in hair count over time, with no significant difference between experienced and novice hair counters. The positive placebo effect seen in prior studies may be due to irregular placement of target areas rather than inexperience of the observers. Topical minoxidil has been shown to be effective in promoting hair growth in men with androgenetic alopecia.

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research Quantitative Assessment of 2% Topical Minoxidil in the Treatment of Male Pattern Baldness

31 citations , January 1989 in “Clinical and Experimental Dermatology”

In this study, topical 2% minoxidil did not significantly improve hair density measures in men with male pattern baldness, although there was no deterioration, suggesting a potential prophylactic effect.

research Androgenetic Alopecia: Treatment Results with Topical Minoxidil

39 citations , March 1987 in “Journal of The American Academy of Dermatology”

Topical minoxidil is a safe and effective treatment for hair loss caused by androgenetic alopecia.

research Safety and Efficacy of Topical Minoxidil in the Management of Androgenetic Alopecia

67 citations , March 1987 in “Journal of The American Academy of Dermatology”

This study found that both 2% and 3% minoxidil resulted in a significant increase in hair counts for participants with androgenetic alopecia over 12 months.

research Reply

1 citations , January 1987 in “Journal of The American Academy of Dermatology”

The patient's hair loss was likely not caused by beta blockers but possibly by stress or other factors.

Dose-Response Study of Topical Minoxidil in Male Pattern Baldness

research Topical Minoxidil in Early Male Pattern Baldness

138 citations , August 1985 in “Journal of The American Academy of Dermatology”

Minoxidil promotes hair growth in male pattern baldness.

research Topical Minoxidil Therapy in Hereditary Androgenetic Alopecia

55 citations , February 1985 in “Archives of Dermatology”

In this randomized trial, topical minoxidil treatment resulted in cosmetically acceptable hair growth in 32% of men with hereditary male pattern baldness, with no serious side effects reported.