Roxithromycin Antagonizes Catagen Induction in Murine and Human Hair Follicles: Implication of Topical Roxithromycin as Hair Restoration Reagent

September 2008 in “ Archives of Dermatological Research ”

Toshimitsu Ito, Hidekazu Fukamizu, Natsuho Ito, Naohiro Seo, Hiroaki Yagi, Masahiro Takigawa, Hideo Hashizume

Roxithromycin catagen induction hair follicles topical roxithromycin hair restoration androgenetic alopecia AGA hair loss RXM hair growth topical RXM

TLDR Roxithromycin, an antibiotic, can increase hair growth and might be used as a treatment for hair loss.

In 2009, a study was conducted to investigate the effects of Roxithromycin (RXM), an antibiotic, on hair growth in human and murine hair follicles. The study found that RXM prevented cell death in hair follicles, leading to increased hair growth. It also inhibited catagen-like changes, a phase where hair growth slows, in these follicles. A topical 5% RXM solution restored hair growth in about half of the individuals with androgenetic alopecia (AGA) without any adverse effects. The study concluded that RXM could potentially be used as a treatment for AGA and other types of hair loss. However, the document did not provide the number of subjects involved in the study.

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