A Model System to Analyze the Ability of Human Keratinocytes to Form Hair Follicles

    April 2014 in “ Experimental Dermatology ”
    Rajesh L. Thangapazham, Peter Klover, Shaowei Li … Thomas N. Darling
    Studysummary This study observed that earlier-passage keratinocyte cultures led to superior hair follicle neogenesis in dermal-epidermal composites grafted onto immunodeficient mice, suggesting their potential utility in studying human hair follicle development.
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    Research cited in this study 13

    1. Microenvironmental Reprogramming by Three-Dimensional Culture Enables Dermal Papilla Cells to Induce De Novo Human Hair-Follicle Growth Proceedings of the National Academy of Sciences of the United States of America · 2013
    2. Dissociated Human Dermal Papilla Cells Induce Hair Follicle Neogenesis in Grafted Dermal-Epidermal Composites Journal of Investigative Dermatology · 2013
    3. Characterization of Hair Follicle Development in Engineered Skin Substitutes PLOS ONE · 2013
    4. Strategies to Enhance Epithelial-Mesenchymal Interactions for Human Hair Follicle Bioengineering Journal of Dermatological Science · 2013
    5. Morphogenesis of Chimeric Hair Follicles in Engineered Skin Substitutes With Human Keratinocytes and Murine Dermal Papilla Cells Experimental Dermatology · 2012
    6. Sphere Formation Increases the Ability of Cultured Human Dermal Papilla Cells to Induce Hair Follicles from Mouse Epidermal Cells in a Reconstitution Assay Journal of Investigative Dermatology · 2011
    7. Hair Follicles Guide Nerve Migration In Vitro and In Vivo in Tissue-Engineered Skin Journal of Investigative Dermatology · 2011
    8. De Novo Formation and Ultra-Structural Characterization of a Fiber-Producing Human Hair Follicle Equivalent In Vitro Journal of biotechnology · 2011
    9. Review of Hair Follicle Dermal Cells Journal of Dermatological Science · 2009
    10. A Human Folliculoid Microsphere Assay for Exploring Epithelial-Mesenchymal Interactions in the Human Hair Follicle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2008
    11. Hair Morphogenesis In Vitro: Formation of Hair Structures Suitable for Implantation Regenerative Medicine · 2008
    12. Hair Follicle Regeneration Using Grafted Rodent and Human Cells Journal of Investigative Dermatology · 2007
    13. Reorganization of Hair Follicles in Human Skin Organ Culture Induced by Cultured Human Follicle-Derived Cells Experimental Dermatology · 2005

    Related research 6

    1. Induction of Hair Follicle Neogenesis with Cultured Mouse Dermal Papilla Cells in De Novo Regenerated Skin Tissues Journal of Tissue Engineering and Regenerative Medicine · 2019
    2. The Dermal Papilla: An Instructive Niche for Epithelial Stem and Progenitor Cells in Development and Regeneration of the Hair Follicle Cold Spring Harbor Perspectives in Medicine · 2014
    3. A Model System to Analyze the Ability of Human Keratinocytes to Form Hair Follicles Experimental Dermatology · 2014
    4. Dissociated Human Dermal Papilla Cells Induce Hair Follicle Neogenesis in Grafted Dermal-Epidermal Composites Journal of Investigative Dermatology · 2013
    5. Hair Follicle Units Improving the Construction of Tissue Engineered Skin In Vitro Journal of Tissue Engineering and Reconstructive Surgery · 2013
    6. Reorganization of Hair Follicles in Human Skin Organ Culture Induced by Cultured Human Follicle-Derived Cells Experimental Dermatology · 2005