An Investigation of Apoptosis in Androgenetic Alopecia

    June 2002 in “ American Journal of Dermatopathology ”
    Shawn E. Cowper, Arlene S. Rosenberg, Michael J. Morgan
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    TLDR Apoptosis contributes to hair loss in androgenetic alopecia.
    This document is a compilation of four different studies investigating the role of apoptosis (cell death) in androgenetic alopecia (AGA). The studies analyzed scalp biopsies from male cadavers with AGA and found differences in bcl-2 expression between affected and unaffected areas of the scalp, as well as differences in bcl-2 staining indices between frontal and occipital follicles. The studies suggest that apoptosis plays a role in the development of AGA, but further research is needed to fully understand the mechanism.
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