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research LB1029 The common fragrance, linalool, promotes core hair follicle pathology events associated with frontal fibrosing alopecia through activating a cognate olfactory receptor in the bulge

July 2024 in “Journal of Investigative Dermatology”

Linalool in fragrances may harm hair follicles and contribute to hair loss.

Environmental Pathobiology of Frontal Fibrosing Alopecia: Does Linalool Promote FFA Development and Progression?

research 382 Environmental pathobiology of frontal fibrosing alopecia (FFA): Does linalool promote FFA development and progression by inducing epithelial hair follicle stem cell damage and MICA expression in the bulge?

November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study suggests that allergens like linalool found in personal care products may contribute to the pathobiology of frontal fibrosing alopecia by affecting immune responses and stem cell function in hair follicles.

research ESDR382 - Environmental pathobiology of frontal fibrosing alopecia (FFA): Does linalool promote FFA development and progression by inducing epithelial hair follicle stem cell damage and MICA expression in the bulge?

September 2022

Linalool in personal care products may worsen frontal fibrosing alopecia by damaging hair follicle stem cells and triggering harmful immune responses.

research Expression of Keratin 15 in Alopecia's Frontal Hair Follicle

January 2007 in “Zhongguo linchuang yixue”

In this study, researchers observed that Keratin 15 expression in hair follicles was significantly higher in normal adult men compared to those with androgenetic alopecia.

research Primary cutaneous follicle center lymphoma presenting as frontal fibrosing alopecia

September 2025 in “Dermatology Online Journal”

In this case study, a 24-year-old woman with frontal alopecia resembling frontal fibrosing alopecia was ultimately diagnosed with primary cutaneous follicle center lymphoma, highlighting the critical role of biopsy in identifying atypical alopecia presentations.

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Community Join

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community 5ar Type I in the frontal hair follicles - Dutasteride

in Finasteride/Dutasteride 21 upvotes 2 years ago

The conversation discusses that dutasteride may be more effective than finasteride for frontal hair loss due to higher 5ar Type 1 enzyme activity in that area. Some users question the validity of this information, while others confirm it with additional sources.

community Frontal fibrosing alopecia and personal care product use 2023

3 years ago

community Diffuse thinning + frontal receding. Caffeine Shampoo 2 month progress. Will continue updating.

9 upvotes 9 years ago

The user is trying alternative hair loss treatments like caffeine shampoo and dermarolling before considering minoxidil or other advanced treatments, and has noticed an increase in vellus hairs and some strong terminal hairs after two months of daily caffeine shampoo use. They plan to continue the treatment and document progress.

community Follicles finally showing first signs of life

105 upvotes 6 years ago

The post and conversation are about a user seeing hair regrowth after using Rogaine, rosemary oil, pumpkin seed oil, saw palmetto, microneedling, and LLLT. The user plans to add Nizoral soon and is hopeful about continued progress.

community Can you get hair transplants for frontal temple density ? Or would i be more likely to get shock loss

4 upvotes 6 months ago

The user is considering a hair transplant for frontal temple density but is concerned about shock loss. They have been using finasteride for about two years and are advised to consider minoxidil and microneedling for better results.

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