An Investigation of Apoptosis in Androgenetic Alopecia

    January 2003 in “ PubMed ”
    Michael B. Morgan, Paul Rose
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    TLDR Hair loss in men might be linked to programmed cell death.
    The study "An investigation of apoptosis in androgenetic alopecia" conducted by Michael B Morgan et al. in 2002, examined the role of apoptosis (programmed cell death) in androgenetic alopecia (AGA), a common form of hair loss. The study involved 16 male patients with AGA. The researchers used immunohistochemical markers to assess differences in apoptosis between affected and unaffected areas of the scalp. They found significant differences in the expression of the bcl-2 staining index and TUNEL expression, both markers of apoptosis, between the affected (frontal) and unaffected (occipital) areas of the scalp. This suggested that apoptosis might play a role in AGA, although the exact mechanism was not determined.
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