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research Cell death by cornification

375 citations , June 2013 in “Biochimica et biophysica acta. Molecular cell research”

This review examines the process of cornification as a mode of programmed cell death and outlines how keratinocytes activate anti-cell death mechanisms to maintain epidermal homeostasis, but reports no new results.

Cell Death in the Skin: Mechanisms and Implications

research Cell death in the skin

120 citations , February 2009 in “Apoptosis”

This review examines apoptotic and anti-apoptotic mechanisms in skin homeostasis and related diseases but presents no new research findings.

Arctiin Blocks Hydrogen Peroxide-Induced Senescence and Cell Death Through MicroRNA Expression Changes in Human Dermal Papilla Cells

research Arctiin blocks hydrogen peroxide-induced senescence and cell death though microRNA expression changes in human dermal papilla cells

25 citations , September 2014 in “Biological Research”

This study found that arctiin, a compound from Arctium lappa, demonstrated protective effects against oxidative stress-induced dysfunction in human hair dermal papilla cells, suggesting potential therapeutic use for alopecia.

research Genetically Induced Cell Death in Bulge Stem Cells Reveals Their Redundancy for Hair and Epidermal Regeneration

13 citations , December 2014 in “Stem Cells”

This study found that quiescent bulge stem cells, when prevented from contributing to hair follicle and epidermal regeneration, did not affect hair follicle growth or wound healing in the short term.

research Cell death in skin function, inflammation, and disease

12 citations , August 2022 in “Biochemical Journal”

This review discusses the mechanisms of skin-associated cell death and their potential role in treating inflammatory skin diseases, but presents no new clinical findings.

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community [Nov 2019] The peptide AC 2 isolated from Bacillus-treated Trapa japonica fruit extract rescues DHT (dihydrotestosterone)-treated human dermal papilla cells and mediates mTORC1 signaling for autophagy and apoptosis suppression

23 upvotes 6 years ago

A peptide from Japanese water chestnut fruit may help with hair loss by suppressing DHT's effect on hair follicle cell death, potentially serving as a finasteride alternative. The treatment's effectiveness and safety in humans remain uncertain.

community Mallia Aesthetics achieves key regulatory steps for novel sCD83-derived ingredient for hair growth

24 upvotes 1 year ago

Mallia Aesthetics has developed MAL-838, a hormone-free product derived from sCD83, which stimulates hair growth without disrupting the skin microbiome. sCD83 promotes hair growth by activating hair follicles and preventing cell death, offering a localized treatment without systemic side effects.

community Opinions on best microneedling protocol? Some thoughts...

11 upvotes 3 years ago

Microneedling can enhance hair growth by improving minoxidil absorption and stimulating blood flow. Users discuss optimal needle depths, with some favoring shallow frequent needling for better absorption and others preferring deeper needling for stem cell activation.

community Microneedling depth. Does one length fit all areas of the scalp? Maybe not.

55 upvotes 4 years ago

Microneedling depth should be customized based on hair type and scalp area, with many users finding 0.5-0.6mm effective for miniaturized hairs to avoid damage. Users report varying pain levels and results, with some preferring shorter needle lengths and others using longer ones like 1.75mm for scalp health and density improvement.

community Is stem cell + PRP therapy legit?

13 upvotes 8 years ago

Stem cell and PRP therapy for hair loss is considered experimental and not consistently effective. Treatments like finasteride, minoxidil, and hair transplants are more established, but the potential for cloning chemically resistant hair follicles is seen as a promising future solution.

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