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      learn Fluridil

      a topical anti-androgen with less systemic involvement

      learn Spironolactone

      powerful topical and oral anti-androgen used mostly by women

      learn Clascoterone

      a novel topical treatment that inhibits DHT on androgen receptors

      learn RU58841

      a potent but unapproved and potentially problematic topical anti-androgen

      learn Melatonin

      hormone commonly taken for sleep aid has some topical benefits for hair

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      community Topical 5% Min - 2% Keto shampoo - 4 months update - 26M out

      in Is this regrowth?  10 upvotes 23 hours ago
      A 26-year-old male experiencing hair loss since 2020 is using topical 5% Minoxidil and 2% Ketoconazole shampoo for four months, still experiencing significant shedding. He is considering cutting his hair short and has not yet started DHT blockers like Finasteride or Dutasteride.

      community Topical Finasteride 2 year update

      in Progress Pictures  730 upvotes 2 days ago
      The user reported significant improvement in hair quality and stability using topical finasteride for two years, without side effects. They later added minoxidil, which may have further enhanced hair quality.

      community Sensitive liver, topical fin safe to try?

      in Finasteride  98 upvotes 5 days ago
      Topical finasteride is considered safer for the liver than oral finasteride due to less systemic absorption, but regular liver function tests are advised. The user is concerned about liver health due to a history of NAFLD and is exploring topical finasteride as a safer alternative.