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research Roxithromycin antagonizes catagen induction in murine and human hair follicles: implication of topical roxithromycin as hair restoration reagent

15 citations , September 2008 in “Archives of Dermatological Research”

In this study, topical 5% roxithromycin was effective in restoring hair growth in about half of individuals with androgenetic alopecia without causing adverse effects.

research Can antibiotic‐induced changes in the composition of the hair follicle microbiome regulate human hair growth?

4 citations , April 2021 in “Experimental Dermatology”

This study shares preliminary findings that roxithromycin treatment tendentially increased hair shaft production and altered the hair follicle microbiota in human hair ex vivo, with substantial inter-individual differences observed.

research New investigational drugs for androgenetic alopecia

48 citations , April 2013 in “Expert Opinion on Investigational Drugs”

This article reviews emerging treatments for androgenetic alopecia, including topical 5-alpha-reductase inhibitors and prostaglandin modulators, but reports no clinical results and calls for further efficacy evidence, especially for PRP.

research Discount pharmacies may save patients significant money on androgenetic alopecia medications compared to both traditional pharmacies and direct-to-consumer companies

March 2025 in “Journal of the American Academy of Dermatology”

Discount pharmacies offer cheaper options for hair loss medications than traditional or direct-to-consumer pharmacies.

research Emerging Topical and Systemic JAK Inhibitors in Dermatology

277 citations , December 2019 in “Frontiers in Immunology”

This review discusses the immunological basis and development of Janus kinase inhibitors for treating skin diseases and reports no new clinical findings.

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Community Join

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community Stop the fear mongering of oral minoxidil its one of the best treatments available in 2020. It does not cause heart lesions or adverse cardiac effects like people claim. I am maintaining with just oral minoxidil with retrograde alopecia and diffuse thinning all over nw3 hairline

78 upvotes 6 years ago

Oral minoxidil is considered a safe and effective treatment for hair loss at low dosages, with minimal cardiac risks. Users report positive results, though some experience side effects like increased heart rate and skin changes, and consulting a doctor is advised.

community Topical minoxidil routine and shampooing frequency

4 upvotes 5 days ago

The user applies 10% minoxidil nightly, takes 1mg finasteride, multivitamins, and a hair growth serum, and is concerned about over-washing hair with dermatologist-recommended shampoo. It is suggested to shampoo every other day and rinse with water on alternate days unless otherwise advised by a dermatologist.

community Topical min 13 months and oral fin 6 months, progress

11 upvotes 5 days ago

The user has been using topical minoxidil for 13 months and oral finasteride for 6 months to address hair loss after a hair transplant. They plan to switch to oral minoxidil for better results and occasionally use topical minoxidil and microneedling.

community F23 does Topical Min work on vellus hairs?

in Female 72 upvotes 1 week ago

Topical minoxidil 5% may help turn vellus hairs into normal-looking hairs, but results can vary, especially on the temples. The user stopped testosterone injections and finasteride, which may have affected hair recovery.

community Topical dutasteride + minox + oral fin 1mg/day

7 upvotes 1 week ago

The conversation discusses hair regrowth using topical dutasteride, minoxidil, and oral finasteride 1mg/day. The user reports seeing new hair growth.

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Learn

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learn Finasteride

Topical or oral? Choosing between pills and lotions according to your case. In studies, topical finasteride gave much lower blood levels of the drug than tablets but still lowered blood DHT, and whether it causes fewer side effects has not been established. There is no FDA-approved topical finasteride, and the FDA warned about compounded versions in April 2025.

learn Cetirizine

Is topical cetirizine effective for androgenetic alopecia in women? Topical cetirizine is not an approved product and its use for female-pattern hair loss is off-label. The evidence is one small pilot study in mixed-sex patients and one randomized trial in 66 women where cetirizine was added to minoxidil; it is unproven on its own.

learn Glycerin

Does topical glycerin have any effect on hair thickness or follicle function? Topical glycerin mainly hydrates the hair and scalp; no study has shown that it increases hair thickness or changes follicle function.

learn Valproic acid

How is valproic acid being explored differently in topical hair products compared to its traditional oral medical use? Topical valproic acid is being studied for local effects on the hair follicle rather than the whole-body effects of the oral drug. The human evidence is one small randomized 24-week trial of an 8.3% spray; no topical valproate product is approved for hair loss.

learn Vitamin B12

Can topical products containing Vitamin B12 improve scalp health and hair growth? Topical Vitamin B12 may not significantly improve hair growth unless there's a deficiency.

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