Formulation and Evaluation of Hair Gel for the Treatment of Chronic Inflammatory Disorder Seborrheic Dermatitis
January 2013
New to Ketoconazole? There is a guide in the encyclopedia. Read the guide → Studysummary This study reported that the HG3 formulation of a Ketoconazole anti-dandruff gel exhibited superior drug release and antifungal efficacy without causing skin irritation, compared to other formulations tested. Our plain-language summary of this paper — not a Tressless recommendation.
The study focused on formulating and evaluating Ketoconazole anti-dandruff hair gels for treating seborrheic dermatitis, aiming for prolonged antidandruff action. Various formulations were assessed for active content, physical appearance, pH, viscosity, extrudability, antifungal activity, drug release profile, and stability. The HG3 formulation demonstrated superior drug release and higher antimicrobial efficacy without causing dermal irritation or inflammation, making it the most effective among the tested formulations.
