Formulation and Evaluation of Hair Gel for the Treatment of Chronic Inflammatory Disorder Seborrheic Dermatitis

The study focused on formulating and evaluating Ketoconazole anti-dandruff hair gels for treating seborrheic dermatitis, aiming for prolonged antidandruff action. Various formulations were assessed for active content, physical appearance, pH, viscosity, extrudability, antifungal activity, drug release profile, and stability. The HG3 formulation demonstrated superior drug release and higher antimicrobial efficacy without causing dermal irritation or inflammation, making it the most effective among the tested formulations.