Comparison Between 5% Minoxidil Plus 2% Flutamide Solution vs. 5% Minoxidil Solution in the Treatment of Androgenetic Alopecia

    February 2022 in “ Journal of Cosmetic Dermatology ”
    Gita Faghihi, Fariba Iraji, Amir Hossein Siadat … Maedeh Sadat Hoseyni
    Studysummary In this study, a combination treatment of topical 2% flutamide and 5% minoxidil significantly improved hair density, hair thickness, and patient satisfaction more than 5% minoxidil alone in patients with androgenetic alopecia over six months.
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    Research cited in this study 13

    1. Treatment Options for Androgenetic Alopecia: Efficacy, Side Effects, Compliance, Financial Considerations, and Ethics Journal of Cosmetic Dermatology · 2021
    2. Minoxidil And Its Use In Hair Disorders: A Review Drug Design Development and Therapy · 2019
    3. A Randomized, Double-Blind Controlled Study of the Efficacy and Safety of Topical Solution of 0.25% Finasteride Admixed with 3% Minoxidil vs. 3% Minoxidil Solution in the Treatment of Male Androgenetic Alopecia Journal of The European Academy of Dermatology and Venereology · 2018
    4. The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis Journal of The American Academy of Dermatology · 2017
    5. Histological Assessment of Follicular Delivery of Flutamide by Solid Lipid Nanoparticles: Potential Tool for the Treatment of Androgenic Alopecia Drug Development and Industrial Pharmacy · 2015
    6. Clinical Utility and Validity of Minoxidil Response Testing in Androgenetic Alopecia Dermatologic Therapy · 2014
    7. Androgenetic Alopecia: An Evidence-Based Treatment Update American Journal of Clinical Dermatology · 2014
    8. A Randomized Evaluator Blinded Study of Effect of Microneedling in Androgenetic Alopecia: A Pilot Study International Journal of Trichology · 2013
    9. Depressive Symptoms and Suicidal Thoughts Among Former Users of Finasteride With Persistent Sexual Side Effects The Journal of Clinical Psychiatry · 2012
    10. Prospective Cohort Study on the Effects and Tolerability of Flutamide in Patients with Female Pattern Hair Loss Annals of Pharmacotherapy · 2011
    11. Persistent Sexual Side Effects of Finasteride for Male Pattern Hair Loss The Journal of Sexual Medicine · 2011
    12. Finasteride in the Treatment of Men with Frontal Male Pattern Hair Loss Journal of The American Academy of Dermatology · 1999
    13. Photographic Documentation of Hair Growth in Androgenetic Alopecia Dermatologic Clinics · 1999

    Related research 10

    1. Comparison Between 5% Minoxidil Plus 2% Flutamide Solution vs. 5% Minoxidil Solution in the Treatment of Androgenetic Alopecia Journal of Cosmetic Dermatology · 2022
    2. Treatment of Female Pattern Hair Loss PubMed · 2012
    3. The Therapeutic Progress of Androgenetic Alopecia Journal of Practical Dermatology · 2012
    4. Treatment of Female Pattern Hair Loss with the Androgen Receptor Antagonist Flutamide Australasian Journal of Dermatology · 2011
    5. The Anti-Androgen Combination, Flutamide Plus Finasteride, Paradoxically Suppressed LH and Androgen Concentrations in Pregnant Spotted Hyenas, but Not in Males General and Comparative Endocrinology · 2010
    6. Finasteride Treatment of Hair Loss in Women Annals of Pharmacotherapy · 2010
    7. Therapy of Alopecia: Psychological Impact and Treatments Farmaceutski glasnik · 2005
    8. Treatment of Hyperandrogenic Alopecia in Women Obstetrical & Gynecological Survey · 2003
    9. Local and Systemic Reduction by Topical Finasteride or Flutamide of Hamster Flank Organ Size and Enzyme Activity Journal of Investigative Dermatology · 1995
    10. Effects of Flutamide and Finasteride on Rat Testicular Descent Endocrinology · 1991