Clinical Utility and Validity of Minoxidil Response Testing in Androgenetic Alopecia

August 2014 in “ Dermatologic Therapy ”

Andy Goren, Jerry Shapiro, Janet L. Roberts, John D. McCoy, Nisha Desai, Z Zarrab, Aldona Pietrzak, Torello Lotti

minoxidil androgenetic alopecia minoxidil response testing Rogaine AGA

TLDR Minoxidil response testing helps treat hair loss effectively and safely.

The study confirms the clinical validity of minoxidil response testing in treating androgenetic alopecia (AGA) and demonstrates its clinical utility in guiding AGA treatment. The test could protect consumers from the potential side effects, emotional stress, and expense associated with the use of an ineffective drug. Minoxidil response testing could also direct patients to seek medical consultation earlier and ultimately improve outcomes for AGA patients.

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Research cited in this study

7 / 7 results

Sulfotransferase Activity in Plucked Hair Follicles Predicts Response to Topical Minoxidil in the Treatment of Female Androgenetic Alopecia

research Sulfotransferase Activity in Plucked Hair Follicles Predicts Response to Topical Minoxidil in the Treatment of Female Androgenetic Alopecia

20 citations, April 2014 in “Dermatologic Therapy”

Sulfotransferase in hair follicles helps predict how well minoxidil works for female hair loss.

research Novel Enzymatic Assay Predicts Minoxidil Response in the Treatment of Androgenetic Alopecia

27 citations, November 2013 in “Dermatologic Therapy”

New test predicts if hair loss treatment will work.

A Multicenter, Randomized, Placebo-Controlled, Double-Blind Clinical Trial of a Novel Formulation of 5% Minoxidil Topical Foam Versus Placebo in the Treatment of Androgenetic Alopecia in Men

research A Multicenter, Randomized, Placebo-Controlled, Double-Blind Clinical Trial of a Novel Formulation of 5% Minoxidil Topical Foam Versus Placebo in the Treatment of Androgenetic Alopecia in Men

142 citations, August 2007 in “Journal of The American Academy of Dermatology”

New 5% minoxidil foam effectively promotes hair growth and is safe for use.

A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men

research A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men

269 citations, August 2002 in “Journal of The American Academy of Dermatology”

5% minoxidil works better for hair growth and density, with minor irritation.

research Sulfation of Minoxidil by Multiple Human Cytosolic Sulfotransferases

59 citations, February 1998 in “Chemico-Biological Interactions”

Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.

research Minoxidil Sulfation in the Hair Follicle

32 citations, January 1994 in “Skin Pharmacology and Physiology”

Minoxidil helps hair growth by activating enzymes in hair follicles.

research Minoxidil Sulfate Is the Active Metabolite That Stimulates Hair Follicles

166 citations, November 1990 in “Journal of Investigative Dermatology”

Minoxidil sulfate stimulates hair growth.

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community Not everyone should immediately go on Fin if they are starting to bald

in Finasteride/Dutasteride 21 upvotes 11 months ago

The conversation suggests that people should consult a dermatologist to understand their type of hair loss before starting treatments like finasteride or dutasteride, especially if they have autoimmune issues or low DHT. Some participants believe in starting treatment like finasteride immediately if hair loss is due to DHT, while others recommend ruling out other causes and considering minoxidil first, especially for younger individuals.

community I am a dermatologist with a clinical interest in alopecia. AMA

in Will treatment work for me? 2 years ago

In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

community 2024 Official beginner guide for “I’m losing my hair, what can I do?”

in General 726 upvotes 4 months ago

For hair loss, start with Finasteride, Minoxidil, Ketoconazole shampoo, and Microneedling. For severe cases, consider Dutasteride, oral Minoxidil, or hair transplants.

community Do we know exactly why some people respond so great to dut/fin,min and others dont?

in Research/Science 29 upvotes 1 month ago

Genetic factors, enzyme activity, and DHT sensitivity affect individual responses to hair loss treatments like finasteride, minoxidil, and dutasteride. Starting treatments early can slow hair loss, but results vary among individuals.

community Why is Minoxidil not enough for hair loss? (No fin)

in Minoxidil 57 upvotes 6 days ago

Minoxidil alone is often insufficient for treating hair loss because it doesn't address the DHT-related cause. Combining it with finasteride, a DHT blocker, is generally more effective.

community I bought a microscope, how does my scalp/hairs look? I've been suffering diffuse thinning and hair loss after covid and never recovered (2 yrs ago) I eat healthy, in shape and workout.

in Progress Pictures 86 upvotes 9 months ago

A person with hair loss since COVID-19 is considering treatments like finasteride and minoxidil but is hesitant due to potential side effects. Suggestions include visiting a dermatologist, using a ketoconazole shampoo, and considering that post-COVID hair loss might be an autoimmune response.

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research Pustular Dermatosis of the Scalp Due to Topical Minoxidil 5%

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A woman had an unusual allergic reaction to a hair loss treatment, which cleared up after stopping the treatment and using a different medication.

research Effectivity of Minoxidil as a Treatment for Alopecia Areata

January 2014 in “DOAJ (DOAJ: Directory of Open Access Journals)”

Minoxidil can effectively treat patchy hair loss by stimulating hair growth.

research Alopecia Areata Treated With Topical Minoxidil

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Topical minoxidil can help hair regrowth in alopecia areata patients, but maintaining the growth after stopping treatment is inconsistent.