Clinical Utility and Validity of Minoxidil Response Testing in Androgenetic Alopecia

August 2014 in “ Dermatologic Therapy ”

Andy Goren, Jerry Shapiro, Janet L. Roberts, John D. McCoy, Nisha Desai, Z Zarrab, Aldona Pietrzak, Torello Lotti

minoxidil androgenetic alopecia minoxidil response testing Rogaine AGA

TLDR Minoxidil response testing helps treat hair loss effectively and safely.

The study confirms the clinical validity of minoxidil response testing in treating androgenetic alopecia (AGA) and demonstrates its clinical utility in guiding AGA treatment. The test could protect consumers from the potential side effects, emotional stress, and expense associated with the use of an ineffective drug. Minoxidil response testing could also direct patients to seek medical consultation earlier and ultimately improve outcomes for AGA patients.

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Research cited in this study

7 / 7 results

Sulfotransferase Activity in Plucked Hair Follicles Predicts Response to Topical Minoxidil in the Treatment of Female Androgenetic Alopecia

research Sulfotransferase Activity in Plucked Hair Follicles Predicts Response to Topical Minoxidil in the Treatment of Female Androgenetic Alopecia

20 citations, April 2014 in “Dermatologic Therapy”

Sulfotransferase in hair follicles helps predict how well minoxidil works for female hair loss.

research Novel Enzymatic Assay Predicts Minoxidil Response in the Treatment of Androgenetic Alopecia

27 citations, November 2013 in “Dermatologic Therapy”

New test predicts if hair loss treatment will work.

A Multicenter, Randomized, Placebo-Controlled, Double-Blind Clinical Trial of a Novel Formulation of 5% Minoxidil Topical Foam Versus Placebo in the Treatment of Androgenetic Alopecia in Men

research A Multicenter, Randomized, Placebo-Controlled, Double-Blind Clinical Trial of a Novel Formulation of 5% Minoxidil Topical Foam Versus Placebo in the Treatment of Androgenetic Alopecia in Men

142 citations, August 2007 in “Journal of The American Academy of Dermatology”

New 5% minoxidil foam effectively promotes hair growth and is safe for use.

A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men

research A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men

269 citations, August 2002 in “Journal of The American Academy of Dermatology”

5% minoxidil works better for hair growth and density, with minor irritation.

research Sulfation of Minoxidil by Multiple Human Cytosolic Sulfotransferases

59 citations, February 1998 in “Chemico-Biological Interactions”

Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.

research Minoxidil Sulfation in the Hair Follicle

32 citations, January 1994 in “Skin Pharmacology and Physiology”

Minoxidil helps hair growth by activating enzymes in hair follicles.

research Minoxidil Sulfate Is the Active Metabolite That Stimulates Hair Follicles

166 citations, November 1990 in “Journal of Investigative Dermatology”

Minoxidil sulfate stimulates hair growth.

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For hair loss, start with Finasteride, Minoxidil, Ketoconazole shampoo, and Microneedling. For severe cases, consider Dutasteride, oral Minoxidil, or hair transplants.

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