Addressing Androgenetic Alopecia: A Complex Disorder with a Multilateral Treatment Strategy

    Brijeshkumar Patel, Maria Valéria Robles Velasco, Fern, o Tamez Gutierrez, Daniel Khesin
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    TLDR Treating hair loss effectively may require a multi-sided approach, using different treatments together, and topical treatments could be more effective and safer than oral ones.
    The 2017 review "Addressing Androgenetic Alopecia-A Complex Disorder-with a Multilateral Treatment Strategy" discussed the multifaceted nature of androgenetic alopecia (AGA), a hair loss disorder influenced by factors such as heredity, hormones, inflammation, infections, nutrition, and environment. The authors emphasized the role of dihydrotestosterone (DHT) in AGA, with high DHT levels linked to hair loss. They discussed FDA-approved treatments, minoxidil and finasteride, noting their varying effectiveness and potential side effects. The authors suggested a multilateral therapeutic approach, addressing multiple pathophysiological pathways, could be more effective than a single-drug approach. They also proposed that topical treatments could target hair follicles more effectively and with fewer side effects than oral treatments. Other potential treatments such as Alfatradiol, Dutasteride, β-sitosterol, Canadian willow herb extract, Fluridil, Ketoconazole, Prostaglandin F2a analogues, melatonin, and cetirizine were also discussed. The role of Vitamin D and Zinc in hair growth was also highlighted.
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      community What else is good. Besides the big 3.

      in Chat  34 upvotes 2 months ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

      community Why is it that low testosterone causes hair loss as well? How can I be balding?

      in Chat  158 upvotes 8 months ago
      The conversation discusses the confusion over low testosterone potentially causing hair loss, with users sharing personal experiences and knowledge about hair loss treatments like Finasteride. Some users suggest that hair follicle sensitivity to DHT, not testosterone levels, is the key factor in balding, and others discuss the side effects of hair loss medications.

      community When are we getting a cure to hair loss?

      in Chat 1 year ago
      Potential treatments for hair loss, including Minoxidil, finasteride, RU58841 and various upcoming pharmaceuticals, gene editing and cloning. It is suggested that a cure, if found, would be highly profitable due to the large number of people affected by hair loss globally.

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