Androgen-Dependent Beard Dermal Papilla Cells Secrete Autocrine Growth Factors in Response to Testosterone Unlike Scalp Cells

    November 1998 in “ ˜The œjournal of investigative dermatology/Journal of investigative dermatology ”
    M. Julie Thornton, Kazuto Hamada, A.G. Messenger, Valerie A. Randall
    Studysummary In this study, researchers found that while both beard and scalp dermal papilla cells release similar autocrine growth factors, only beard cells increased production and response with testosterone, suggesting these factors enhance androgen-induced hair growth.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on jidonline.org →
    Discuss this study in the Community →

    Research cited in this study 11

    1. Balding Hair Follicle Dermal Papilla Cells Contain Higher Levels of Androgen Receptors Than Those From Non-Balding Scalp Journal of Endocrinology · 1998
    2. Ability to Culture Dermal Papilla Cells from Red Deer Hair Follicles with Differing Hormonal Responses In Vivo Offers a New Model for Studying the Control of Hair Follicle Biology ˜The œjournal of experimental zoology/Journal of experimental zoology · 1996
    3. A Comparison of the Culture and Growth of Dermal Papilla Cells from Hair Follicles from Non-Balding and Balding (Androgenetic Alopecia) Scalp British Journal of Dermatology · 1996
    4. Androgen Induction of Follicular Epithelial Cell Growth Is Mediated via Insulin-like Growth Factor-I from Dermal Papilla Cells Biochemical and biophysical research communications · 1995
    5. Interaction Between Dermal Papilla Cells and Follicular Epithelial Cells In Vitro: Effect of Androgen PubMed · 1995
    6. Androgens and Human Hair Growth Clinical endocrinology · 1994
    7. Soluble Factors From Human Hair Papilla Cells And Dermal Fibroblasts Dramatically Increase The Clonal Growth Of Outer Root Sheath Cells Archives of Dermatological Research · 1993
    8. Cultured Dermal Papilla Cells From Androgen-Dependent Human Hair Follicles Contain More Androgen Receptors Than Those From Non-Balding Areas Of Scalp Journal of Endocrinology/Journal of endocrinology · 1992
    9. Quantitative Models for the Study of Hair Growth In Vivo Annals of the New York Academy of Sciences · 1991
    10. The In Vitro Properties of Dermal Papilla Cell Lines Established From Human Hair Follicles British Journal of Dermatology · 1986
    11. Modulation of Dermal Cell Activity During Hair Growth in the Rat Journal of Cutaneous Pathology · 1975