Search

for
Search:

Research

5 / 1000+ results

research Androgen-Dependent Beard Dermal Papilla Cells Secrete Autocrine Growth Factor(s) in Response to Testosterone Unlike Scalp Cells

51 citations , November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology”

In this study, researchers found that while both beard and scalp dermal papilla cells release similar autocrine growth factors, only beard cells increased production and response with testosterone, suggesting these factors enhance androgen-induced hair growth.

research Disorders of hair in infants and children other than alopecia

13 citations , January 2002 in “Clinics in dermatology”

This study found that AHCC supplementation significantly reduced alopecia severity in Ara-C treated rats and mitigated liver injury-related side effects in mice treated with 6-MP and MTX.

research Animal models of androgen-dependent disorders of the pilosebaceous apparatus

38 citations , July 1989 in “Archives of dermatological research”

Testosterone causes hair loss in AGA mice, which are good for testing baldness treatments, and both minoxidil and cyproterone acetate can prevent this hair loss.

Androgens Affect the Activity of Human Sebocytes in Culture Depending on the Localization of the Sebaceous Glands, and Their Effect Is Antagonized by Spironolactone

research Androgens Affect the Activity of Human Sebocytes in Culture in a Manner Dependent on the Localization of the Sebaceous Glands and Their Effect Is Antagonized by Spironolactone

40 citations , January 1994 in “Skin Pharmacology and Physiology”

This study found that testosterone and 5α-dihydrotestosterone affect human sebocytes differently depending on the skin region, with spironolactone inhibiting their proliferation and counteracting androgen effects in facial sebocytes.

research Osteopontin Gene is Expressed in the Dermal Papilla of Pelage Follicles in a Hair-Cycle-Dependent Manner

17 citations , December 2001 in “Journal of Investigative Dermatology”

This study found that osteopontin mRNA is abundantly expressed in dermal papilla cells during the catagen phase of hair growth in rats, suggesting a role in this phase.

View more "androgen-dependent hair disorders" in research →

Community Join

5 / 1000+ results

community Sugar and Hair loss connections

in Research/Science 41 upvotes 1 year ago

High sugar diets may worsen hair loss by increasing 5α-reductase activity and androgen levels, especially in women with PCOS. A low sugar diet might reduce scalp DHT levels, similar to finasteride, but genetics also significantly influence hair loss.

community Hair Loss Ruins Your Mind: 10x rate of BDD. PF S is not real

in Research/Science 39 upvotes 7 months ago

Hair loss is linked to a higher rate of body dysmorphic disorder (BDD), OCD, and depression. Finasteride and dutasteride are not linked to increased suicidal risk, though some users report mental health side effects.

community My Theory Of Androgenic Alopecia

16 upvotes 10 months ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

63 upvotes 2 years ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community Ladies who losing hair early- how young is too young for losing hair? I noticed a lot of hair loss when hitting 30.

5 upvotes 9 years ago

A woman experiencing hair loss at 30 discusses treatments like Rogaine (Minoxidil) and Spironolactone. Others share experiences with hair loss, mentioning treatments like Minoxidil, Nizoral, and scalp oils.

View more "androgen-dependent hair disorders" in community →

Learn

7 / 801 results

learn Cyproterone

a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Overview

learn Stem Cell Factor

learn TDM-105795

What types of alopecia or hair loss conditions might TDM-105795 be designed to target based on current research? TDM-105795 may target non-scarring alopecia, particularly androgenetic alopecia.
How does TDM-105795 differ from more established hair loss ingredients when included in experimental or emerging treatments? TDM-105795 targets thyroid hormone receptors, differing from established treatments like minoxidil and finasteride.

learn Pyrilutamide

highly targeted anti-androgen that might have minimal systemic effects

learn Finasteride

Does hair strand thickness decrease in men with androgenic alopecia? Can finasteride help restore it? Androgenic alopecia thins hair strands by miniaturizing follicles. The pivotal finasteride trials (1,553 men, 1 mg/day, two years) report increased hair counts and improved assessed appearance, but they measured density, not the diameter of individual strands, so the effect on thickness itself is not established.

View more "androgen-dependent hair disorders" in learn →

Clinics

1 / 1 results

70
Trichology
The Pharmacy for Hair Loss & Scalp Disorders, PLLC.Brentwood, TN · US

Experts

1 / 5 results

Unscored
SMP Specialist
Hairo Fallas
Newark, NJ, United States

Hairo Fallas