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Glossary Prostate Cancer

cancer that develops in the prostate gland in men

Prostate cancer, also known as prostatic carcinoma, is a type of cancer that occurs in the prostate gland, which is a small walnut-shaped gland in men that produces seminal fluid. It is one of the most common types of cancer in men and can range from slow-growing tumors that may not cause significant harm to aggressive forms that can spread quickly to other parts of the body. Early detection through screening methods like PSA (Prostate-Specific Antigen) tests and digital rectal exams can improve treatment outcomes.

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Research

5 / 1000+ results

research ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer

224 citations , February 2013 in “The Journal of clinical investigation/The journal of clinical investigation”

This study identifies SOX9 as a critical downstream effector of ERG in TMPRSS2:ERG fusion-positive prostate cancer, indicating its role in tumor invasion and growth.

research A Review on the Clinical Utility of PSA in Cancer Prostate

154 citations , March 2012 in “Indian Journal of Surgical Oncology”

This review re-evaluates the role of Serum Prostate Specific Antigen in prostate cancer diagnosis, suggesting it is most reliable for detecting cancer recurrences after treatment.

research The Risks and Benefits of 5α-Reductase Inhibitors for Prostate-Cancer Prevention

147 citations , June 2011 in “New England journal of medicine/The New England journal of medicine”

This review discusses the potential benefits and risks of 5α-reductase inhibitors in preventing prostate cancer and reports no new results.

research Sex differences in SARS-CoV-2 infection rates and the potential link to prostate cancer

113 citations , July 2020 in “Communications biology”

This review suggests that understanding the biological and molecular reasons for more severe COVID-19 in men, particularly those at risk for prostate cancer, could improve management of these patients, but reports no new results.

research Selenium and vitamin E supplements for prostate cancer: evidence or embellishment?

76 citations , April 2002 in “Urology”

This review examines the use of selenium and vitamin E supplements for reducing prostate cancer risk, finding mixed evidence that suggests benefits may be limited to individuals with specific risk factors, like low baseline levels or smoking history, rather than broadly applicable.

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Community Join

5 / 644 results

community Evolution theory: AGA is your body trying to reduce the risk of prostate cancer by exposing your scalp to more UV

in Research/Science 9 months ago

Androgenic alopecia (AGA) might have evolved to reduce prostate cancer risk by increasing UV exposure to the scalp, but this theory is debated. Treatments like minoxidil and finasteride are used for AGA, though the exact causes and evolutionary reasons for hair loss are unclear.

community Pattern hair loss before the age of 35 is associated with higher chances of prostate cancer, cardiovascular diseases, and metabolic syndrome later in life

1075 upvotes 3 months ago

Pattern hair loss before age 35 may be linked to higher risks of prostate cancer, cardiovascular diseases, and metabolic syndrome later in life. Finasteride is discussed as a treatment that may lower PSA levels and potentially prevent prostate issues.

community Fin effects on prostate sensation for MSM

5 upvotes 4 years ago

Finasteride may affect prostate sensation and size, with some users reporting easier urination. Concerns exist about prostate shrinkage even at lower doses.

community Fresh off the press: Dutasteride may cause chronic infertility

in Research/Science 643 upvotes 1 year ago

Dutasteride may cause chronic infertility by reducing semen volume and motility, with concerns about irreversible prostate fibrosis. Users consider switching to finasteride or using treatments like minoxidil and microneedling, weighing hair preservation against fertility.

community Nutrafol backed by Science to reverse male balding?

in Research/Science 1 upvotes 1 year ago

Nutrafol helps improve hair thickness and hairline but may have potential health risks like liver damage and increased prostate cancer risk. The user plans to continue Nutrafol at a lower dosage while managing seborrheic dermatitis and considers future use of topical finasteride, minoxidil, rosemary oil, and microneedling.

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Learn

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learn Cyproterone

a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

Is cyproterone only for women, or can men use it too? Cyproterone acetate is not a women-only drug — published reports describe use in men for prostate cancer, paraphilic disorders and gender-affirming therapy — but it is not FDA-approved for any indication, and European regulators restricted higher doses over a dose-related meningioma risk.

learn Dutasteride

Dutasteride side effects: what the label and studies actually report The Avodart label reports impotence in 4.7% and decreased libido in 3.0% of men in the first six months (1.7% and 1.4% on placebo), with new reports falling after month six; those figures come from BPH trials in older men, and the hair-loss trials in younger men run only six months. The label and studies also flag a PSA drop of about half, a small rise in high-grade prostate cancer in one trial, an observational link to depression, and sexual effects that the label says may persist after stopping.

learn Bicalutamide

a nonsteroidal anti-androgen, most commonly used orally for women

learn Overview

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