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    Glossary Prostate Cancer

    cancer that develops in the prostate gland in men

    Prostate cancer, also known as prostatic carcinoma, is a type of cancer that occurs in the prostate gland, which is a small walnut-shaped gland in men that produces seminal fluid. It is one of the most common types of cancer in men and can range from slow-growing tumors that may not cause significant harm to aggressive forms that can spread quickly to other parts of the body. Early detection through screening methods like PSA (Prostate-Specific Antigen) tests and digital rectal exams can improve treatment outcomes.

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    1. ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer 2013 · 224 citations
    2. A Review on the Clinical Utility of PSA in Cancer Prostate Indian Journal of Surgical Oncology · 2012 · 154 citations
    3. The Risks and Benefits of 5α-Reductase Inhibitors for Prostate-Cancer Prevention 2011 · 147 citations
    4. Sex differences in SARS-CoV-2 infection rates and the potential link to prostate cancer Communications biology · 2020 · 113 citations
    5. Selenium and vitamin E supplements for prostate cancer: evidence or embellishment? Urology · 2002 · 76 citations
    6. The Transcriptional Co-Activator cAMP Response Element-Binding Protein-Binding Protein Is Expressed in Prostate Cancer and Enhances Androgen- and Anti-Androgen-Induced Androgen Receptor Function American Journal of Pathology · 2003 · 72 citations
    7. Prostate cancer prevention Cancer · 2007 · 71 citations
    8. Prostate Cancer Early Detection, Version 2.2015 Journal of the National Comprehensive Cancer Network · 2015 · 67 citations
    9. The dihydrotestosterone (DHT) hypothesis of prostate cancer and its therapeutic implications The Prostate · 1986 · 57 citations
    10. Matriptase activation and shedding with HAI-1 is induced by steroid sex hormones in human prostate cancer cells, but not in breast cancer cells American journal of physiology. Cell physiology · 2006 · 56 citations
    11. The evolutionary impact of androgen levels on prostate cancer in a multi-scale mathematical model Biology direct · 2010 · 50 citations
    12. Prostate cancer incidence among finasteride and alpha-blocker users in the Finnish Prostate Cancer Screening Trial British Journal of Cancer · 2009 · 49 citations
    13. 5-α-Reductase inhibitors for prostate cancer chemoprevention: an updated Cochrane systematic review BJUI · 2010 · 44 citations
    14. A powerful method for pleiotropic analysis under composite null hypothesis identifies novel shared loci between Type 2 Diabetes and Prostate Cancer PLOS Genetics · 2020 · 43 citations
    15. Male pattern baldness and the risk of prostate cancer Annals of Oncology · 2011 · 38 citations
    16. Finasteride-its impact on sexual function and prostate cancer Journal of Cutaneous and Aesthetic Surgery · 2009 · 33 citations
    17. Differential expression of steroid 5α-reductase isozymes and association with disease severity and angiogenic genes predict their biological role in prostate cancer Endocrine Related Cancer · 2010 · 30 citations
    18. Baldness, benign prostate hyperplasia, prostate cancer and androgen levels The Aging Male · 2008 · 30 citations
    19. Male pattern baldness and prostate cancer risk in a population-based case–control study Cancer epidemiology · 2010 · 29 citations
    20. Androgenic alopecia is not useful as an indicator of men at high risk of prostate cancer European Journal of Cancer · 2010 · 28 citations
    21. Hormonal prevention of prostate cancer Urologic oncology · 2003 · 28 citations
    22. Relationship of Early-Onset Baldness to Prostate Cancer in African-American Men Cancer Epidemiology, Biomarkers & Prevention · 2013 · 21 citations
    23. Rare Germline Pathogenic Variants Identified by Multigene Panel Testing and the Risk of Aggressive Prostate Cancer Cancers · 2021 · 20 citations
    24. Cardiovascular effects of hormone therapy for prostate cancer Drug Healthcare and Patient Safety · 2015 · 18 citations
    25. Apocrine sweat gland obstruction by antiperspirants allowing transdermal absorption of cutaneous generated hormones and pheromones as a link to the observed incidence rates of breast and prostate cancer in the 20th century Medical Hypotheses · 2009 · 18 citations
    26. Male Pattern Baldness in Relation to Prostate Cancer–Specific Mortality: A Prospective Analysis in the NHANES I Epidemiologic Follow-up Study American Journal of Epidemiology · 2016 · 17 citations
    27. Age-Dependent Associations between Androgenetic Alopecia and Prostate Cancer Risk Cancer Epidemiology, Biomarkers & Prevention · 2012 · 17 citations
    28. Role of 5 alpha-reductase inhibitors in the management of prostate cancer Clinical interventions in aging · 2006 · 15 citations
    29. Androgenetic alopecia at various ages and prostate cancer risk in an equal-access multiethnic case–control series of veterans Cancer Causes & Control · 2013 · 12 citations
    30. The Percentage of Free PSA and Urinary Markers Distinguish Prostate Cancer from Benign Hyperplasia and Contribute to a More Accurate Indication for Prostate Biopsy Biomedicines · 2020 · 11 citations