Age-Dependent Associations Between Androgenetic Alopecia and Prostate Cancer Risk

November 2012 in “ Cancer Epidemiology, Biomarkers & Prevention ”

David A. Muller, Graham G. Giles, Rodney Sinclair, John L. Hopper, Dallas R. English, Gianluca Severi

androgenetic alopecia prostate cancer vertex AA age-dependent association AA

TLDR Early balding at 40 increases prostate cancer risk.

This study investigated the association between androgenetic alopecia (AA) and prostate cancer risk in men. The results showed that vertex AA at age 40 years was associated with earlier age at onset of prostate cancer and increased cumulative probability of prostate cancer up to age 76 years. The study also found that a single, age-invariant estimate of relative risk is insufficient to describe the age-dependent association between AA and risk of prostate cancer.

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Age-Dependent Associations Between Androgenetic Alopecia and Prostate Cancer Risk

Research cited in this study

research Male Pattern Baldness and the Risk of Prostate Cancer

research Androgenic Alopecia Is Not Useful as an Indicator of Men at High Risk of Prostate Cancer

research Male Pattern Baldness and Prostate Cancer Risk in a Population-Based Case-Control Study

research Baldness, Benign Prostate Hyperplasia, Prostate Cancer, and Androgen Levels

research 5α-Reductase Type 2 Gene Variant Associations with Prostate Cancer Risk, Circulating Hormone Levels, and Androgenetic Alopecia

research Validity of Self-Reported Male Balding Patterns in Epidemiological Studies

research Androgenetic Alopecia: Pathogenesis and Potential for Therapy

research The Psychosocial Consequences of Androgenetic Alopecia: A Review of the Research Literature

research Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia

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