A Genomic Approach to Susceptibility and Pathogenesis Leads to Identifying Potential Novel Therapeutic Targets in Androgenetic Alopecia

March 2017 in “ Genomics ”

R. Dey-Rao, A. K. Sinha

androgenetic alopecia gene expression scalp biopsies apoptosis cell proliferation WNT signaling transcriptional regulators drug targets AGA

TLDR Genomic approach finds new possible treatments for hair loss.

This document discusses a genomic approach to identifying potential therapeutic targets for androgenetic alopecia (AGA). The study analyzed gene expression patterns in scalp biopsies from individuals with AGA and identified several dysregulated pathways and processes, including apoptosis, cell proliferation, and WNT signaling. The study also identified potential transcriptional regulators and drug targets for future AGA therapies. Overall, this study provides insights into the molecular mechanisms underlying AGA and identifies potential targets for future treatments.

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