Androgenetic Alopecia: Identification Of Four Genetic Risk Loci And Evidence For The Contribution Of WNT Signaling To Its Etiology

    January 2013 in “ Journal of Investigative Dermatology ”
    Stefanie Heilmann, Amy K. Kiefer, Nadine Fricker … Markus M. Nöthen
    Studysummary Four genetic risk spots found for hair loss, with WNT signaling involved and a link to curly hair.
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    Research cited in this study 20

    1. Six Novel Susceptibility Loci for Early-Onset Androgenetic Alopecia and Their Unexpected Association with Common Diseases PLOS Genetics · 2012
    2. Regulation of Hair Shedding by the Type 3 IP3 Receptor ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2012
    3. Susceptibility Variants on Chromosome 7p21.1 Suggest HDAC9 as a New Candidate Gene for Male-Pattern Baldness British Journal of Dermatology · 2011
    4. Fine Mapping of the Human AR/EDA2R Locus in Androgenetic Alopecia British Journal of Dermatology · 2010
    5. Common Variants in the Trichohyalin Gene Are Associated with Straight Hair in Europeans American journal of human genetics · 2009
    6. WNT10A Mutations Are a Frequent Cause of a Broad Spectrum of Ectodermal Dysplasias with Sex-Biased Manifestation Pattern in Heterozygotes American journal of human genetics · 2009
    7. Susceptibility Variants for Male-Pattern Baldness on Chromosome 20p11 Nature Genetics · 2008
    8. Male-Pattern Baldness Susceptibility Locus at 20p11 Nature Genetics · 2008
    9. EDA2R Is Associated With Androgenetic Alopecia Journal of Investigative Dermatology · 2008
    10. Genome-Wide Scan and Fine-Mapping Linkage Study of Androgenetic Alopecia Reveals a Locus on Chromosome 3q26 American Journal of Human Genetics · 2008
    11. Hormonal Regulation of Hair Follicles Exhibits a Biological Paradox Seminars in Cell & Developmental Biology · 2007
    12. Scratching the Surface of Skin Development Nature · 2007
    13. Genetic Variation in the Human Androgen Receptor Gene Is the Major Determinant of Common Early-Onset Androgenetic Alopecia American Journal of Human Genetics · 2005
    14. The E211 G>A Androgen Receptor Polymorphism Is Associated With a Decreased Risk of Metastatic Prostate Cancer and Androgenetic Alopecia Cancer Epidemiology, Biomarkers & Prevention · 2005
    15. Genetic Basis of Male Pattern Baldness Journal of Investigative Dermatology · 2003
    16. Androgens and Alopecia Molecular and Cellular Endocrinology · 2002
    17. Androgenetic Alopecia: Pathogenesis and Potential for Therapy Expert Reviews in Molecular Medicine · 2002
    18. The Genetics of Androgenetic Alopecia Clinics in Dermatology · 2001
    19. WNT Signaling in the Control of Hair Growth and Structure Developmental biology · 1999
    20. Diagnostic and Predictive Value of Horizontal Sections of Scalp Biopsy Specimens in Male Pattern Androgenetic Alopecia Journal of The American Academy of Dermatology · 1993