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GlossaryWNT10A

gene crucial for hair, skin, and teeth development

WNT10A is a gene that plays a crucial role in the development and maintenance of various tissues, including hair, skin, and teeth. Mutations in this gene can lead to conditions like hypohidrotic ectodermal dysplasia, which is characterized by sparse hair, missing teeth, and reduced ability to sweat.

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WNT10A Mutations Are a Frequent Cause of a Broad Spectrum of Ectodermal Dysplasias with Sex-Biased Manifestation Pattern in Heterozygotes

research WNT10A Mutations Are a Frequent Cause of a Broad Spectrum of Ectodermal Dysplasias with Sex-Biased Manifestation Pattern in Heterozygotes

197 citations , June 2009 in “American journal of human genetics”

WNT10A mutations often cause ectodermal dysplasias, with males showing more tooth issues than females.

research WNT10A Mutation Causes Ectodermal Dysplasia by Impairing Progenitor Cell Proliferation and KLF4-Mediated Differentiation

96 citations , June 2017 in “Nature Communications”

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

research WNT10A Promotes an Invasive and Self-Renewing Phenotype in Esophageal Squamous Cell Carcinoma

55 citations , March 2015 in “Carcinogenesis”

WNT10A helps esophageal cancer cells spread and keep renewing themselves.

research Evidence for a Functional Interaction of WNT10A and EBF1 in Male-Pattern Baldness

12 citations , September 2021 in “PLoS ONE”

WNT10A and EBF1 interaction affects hair growth in male-pattern baldness.

research Wnt10a as a Candidate for Induction of Dental Pulp Regeneration with Dentine-Inducing Capacity

3 citations , January 2023 in “Journal of Hard Tissue Biology”

Wnt10a may help regenerate dental pulp and form dentine.

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community Better Than Minoxidil? Topical Sodium Valproate

in Research/Science 50 upvotes 9 months ago

Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.

community Natural Remedies: Polyphenols and Hair Loss

22 upvotes 6 years ago

Natural remedies to treat hair loss, such as polyphenols, apple peel extract, grape seed extract, green tea extract, peppermint oil, pumpkin seed oil, apigenin, Ginkgo biloba, red clover extract, olive leaf extract, Ecklonia Cava and Grateloupia elliptica. In addition, terpenes, carotenoids, and tocopherols were discussed as potential treatments.

community Do you keep gains if you stop microneedling?

in Microneedling 15 upvotes 3 months ago

Stopping microneedling may result in losing hair gains, as it enhances the effectiveness of treatments like minoxidil. Combining microneedling with minoxidil and finasteride is more effective than using microneedling alone.