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GlossaryWNT10A

gene crucial for hair, skin, and teeth development

WNT10A is a gene that plays a crucial role in the development and maintenance of various tissues, including hair, skin, and teeth. Mutations in this gene can lead to conditions like hypohidrotic ectodermal dysplasia, which is characterized by sparse hair, missing teeth, and reduced ability to sweat.

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WNT10A Mutations Are a Frequent Cause of a Broad Spectrum of Ectodermal Dysplasias with Sex-Biased Manifestation Pattern in Heterozygotes

research WNT10A Mutations Are a Frequent Cause of a Broad Spectrum of Ectodermal Dysplasias with Sex-Biased Manifestation Pattern in Heterozygotes

197 citations, June 2009 in “American journal of human genetics”

WNT10A mutations often cause ectodermal dysplasias, with males showing more tooth issues than females.

research WNT10A Mutation Causes Ectodermal Dysplasia by Impairing Progenitor Cell Proliferation and KLF4-Mediated Differentiation

96 citations, June 2017 in “Nature Communications”

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

research WNT10A Promotes an Invasive and Self-Renewing Phenotype in Esophageal Squamous Cell Carcinoma

55 citations, March 2015 in “Carcinogenesis”

WNT10A helps esophageal cancer cells spread and keep renewing themselves.

research Alopecia Areata in a Patient with WNT10A Heterozygous Ectodermal Dysplasia

June 2021 in “Dermatology Online Journal”

A girl with a rare genetic condition affecting hair and nails also developed a common type of hair loss, suggesting a possible genetic link.

research Is EBF1 a Negative Regulator of WNT10A in the Development of Androgenetic Alopecia?

September 2017 in “Journal of Investigative Dermatology”

Finasteride helps female-pattern hair loss.

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community Natural Remedies: Polyphenols and Hair Loss

19 upvotes 5 years ago

Natural remedies to treat hair loss, such as polyphenols, apple peel extract, grape seed extract, green tea extract, peppermint oil, pumpkin seed oil, apigenin, Ginkgo biloba, red clover extract, olive leaf extract, Ecklonia Cava and Grateloupia elliptica. In addition, terpenes, carotenoids, and tocopherols were discussed as potential treatments.