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    Glossary WNT10A

    gene crucial for hair, skin, and teeth development

    WNT10A is a gene that plays a crucial role in the development and maintenance of various tissues, including hair, skin, and teeth. Mutations in this gene can lead to conditions like hypohidrotic ectodermal dysplasia, which is characterized by sparse hair, missing teeth, and reduced ability to sweat.

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    Research 10 of 788

    1. Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration Cell · 2011 · 260 citations
    2. WNT10A Mutations Are a Frequent Cause of a Broad Spectrum of Ectodermal Dysplasias with Sex-Biased Manifestation Pattern in Heterozygotes American journal of human genetics · 2009 · 197 citations
    3. WNT10A mutation causes ectodermal dysplasia by impairing progenitor cell proliferation and KLF4-mediated differentiation Nature Communications · 2017 · 96 citations
    4. Identifying novel strategies for treating human hair loss disorders: Cyclosporine A suppresses the Wnt inhibitor, SFRP1, in the dermal papilla of human scalp hair follicles PLOS Biology · 2018 · 68 citations
    5. WNT10A promotes an invasive and self-renewing phenotype in esophageal squamous cell carcinoma Carcinogenesis · 2015 · 55 citations
    6. The role of WNT10B in physiology and disease: A 10-year update Frontiers in Cell and Developmental Biology · 2023 · 27 citations
    7. An investigation of crosstalk between Wnt/β-catenin and transforming growth factor-β signaling in androgenetic alopecia Medicine · 2016 · 18 citations
    8. β-Catenin–Dependent Wnt Signaling: A Pathway in Acute Cutaneous Wounding [RETRACTED] Plastic and Reconstructive Surgery · 2018 · 13 citations
    9. Evidence for a functional interaction of WNT10A and EBF1 in male-pattern baldness PLoS ONE · 2021 · 12 citations
    10. Expression profile analysis of dermal papilla cells mRNA in response to WNT10B treatment Experimental and Therapeutic Medicine · 2019 · 7 citations
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