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    Glossary WNT10A

    gene crucial for hair, skin, and teeth development

    WNT10A is a gene that plays a crucial role in the development and maintenance of various tissues, including hair, skin, and teeth. Mutations in this gene can lead to conditions like hypohidrotic ectodermal dysplasia, which is characterized by sparse hair, missing teeth, and reduced ability to sweat.

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    Research 30 of 788

    1. Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration Cell · 2011 · 260 citations
    2. WNT10A Mutations Are a Frequent Cause of a Broad Spectrum of Ectodermal Dysplasias with Sex-Biased Manifestation Pattern in Heterozygotes American journal of human genetics · 2009 · 197 citations
    3. WNT10A mutation causes ectodermal dysplasia by impairing progenitor cell proliferation and KLF4-mediated differentiation Nature Communications · 2017 · 96 citations
    4. Identifying novel strategies for treating human hair loss disorders: Cyclosporine A suppresses the Wnt inhibitor, SFRP1, in the dermal papilla of human scalp hair follicles PLOS Biology · 2018 · 68 citations
    5. WNT10A promotes an invasive and self-renewing phenotype in esophageal squamous cell carcinoma Carcinogenesis · 2015 · 55 citations
    6. The role of WNT10B in physiology and disease: A 10-year update Frontiers in Cell and Developmental Biology · 2023 · 27 citations
    7. An investigation of crosstalk between Wnt/β-catenin and transforming growth factor-β signaling in androgenetic alopecia Medicine · 2016 · 18 citations
    8. β-Catenin–Dependent Wnt Signaling: A Pathway in Acute Cutaneous Wounding [RETRACTED] Plastic and Reconstructive Surgery · 2018 · 13 citations
    9. Evidence for a functional interaction of WNT10A and EBF1 in male-pattern baldness PLoS ONE · 2021 · 12 citations
    10. Expression profile analysis of dermal papilla cells mRNA in response to WNT10B treatment Experimental and Therapeutic Medicine · 2019 · 7 citations
    11. The fundamentals of WNT10A Differentiation · 2025 · 6 citations
    12. Wnt10a Is a Candidate as a Non-Cellular Agent for Induction of Dental Pulp Regeneration with Dentine-Inducing Capacity. Journal of Hard Tissue Biology · 2023 · 3 citations
    13. Wnt10b Regulation of Hair Follicle Development, Regeneration, and Skin Diseases Stem Cell Reviews and Reports · 2025 · 1 citations
    14. Alopecia areata in a patient with WNT10A heterozygous ectodermal dysplasia Dermatology Online Journal · 2021
    15. Mutational spectrum of EDA, EDAR, EDARADD, and WNT10A genes in the largest cohort of Russian patients with hypohidrotic ectodermal dysplasia Orphanet Journal of Rare Diseases · 2026
    16. WNT10B (wingless-type MMTV integration site family) Atlas of genetics and cytogenetics in oncology and haematology · 2018
    17. 257 Is EBF1 a negative regulator of WNT10A in the development of androgenetic alopecia? Journal of Investigative Dermatology · 2017
    18. Adenovirus-Mediated Wnt10b Overexpression Induces Hair Follicle Regeneration Journal of Investigative Dermatology · 2012 · 77 citations
    19. Wnt signaling in skin organogenesis Organogenesis · 2008 · 72 citations
    20. Treatment of MSCs with Wnt1a-conditioned medium activates DP cells and promotes hair follicle regrowth Scientific Reports · 2014 · 61 citations
    21. The balance of Bmp6 and Wnt10b regulates the telogen-anagen transition of hair follicles Cell Communication and Signaling · 2019 · 35 citations
    22. Wnt10b Promotes Differentiation of Mouse Hair Follicle Melanocytes International Journal of Medical Sciences · 2013 · 29 citations
    23. 3-Deoxysappanchalcone Promotes Proliferation of Human Hair Follicle Dermal Papilla Cells and Hair Growth in C57BL/6 Mice by Modulating WNT/β-Catenin and STAT Signaling Biomolecules & Therapeutics · 2016 · 26 citations
    24. Crosstalk between androgen and Wnt/β-catenin leads to changes of wool density in FGF5-knockout sheep Cell Death and Disease · 2020 · 23 citations
    25. Wnt1a maintains characteristics of dermal papilla cells that induce mouse hair regeneration in a 3D preculture system Journal of Tissue Engineering and Regenerative Medicine · 2015 · 23 citations
    26. Low-level laser treatment stimulates hair growth via upregulating Wnt10b and β-catenin expression in C3H/HeJ mice Lasers in Medical Science · 2017 · 15 citations
    27. LncRNA-PCAT1 maintains characteristics of dermal papilla cells and promotes hair follicle regeneration by regulating miR-329/Wnt10b axis Experimental Cell Research · 2020 · 13 citations
    28. Regulatory Processes of the Canonical Wnt/β-Catenin Pathway and Photobiomodulation in Diabetic Wound Repair International Journal of Molecular Sciences · 2022 · 11 citations
    29. Melatonin Regulates the Periodic Growth of Cashmere by Upregulating the Expression of Wnt10b and β-catenin in Inner Mongolia Cashmere Goats Frontiers in genetics · 2021 · 9 citations
    30. Immunohistochemical study of hair follicle stem cells in regenerated hair follicles induced by Wnt10b International Journal of Medical Sciences · 2016 · 9 citations