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    GlossaryWNT genes

    group of genes producing proteins crucial for cell signaling

    WNT genes are a group of genes that produce proteins involved in signaling pathways crucial for cell growth, development, and differentiation. These pathways play a significant role in various biological processes, including embryonic development and the regulation of hair growth, making them important in both normal physiology and diseases like cancer and alopecia.

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      compound that activates Wnt/β-catenin to promote hair regrowth and create new hair follicles

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      an estrogen promoting hair regrowth more commonly used in women

      learn Follistatin

      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

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      community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

      in Research/Science  92 upvotes 2 years ago
      The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

      community Better Than Minoxidil? Topical Sodium Valproate

      in Research/Science  51 upvotes 1 month ago
      Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.

      community Opinions on Scalp fibrosis and DHT?

      in Research/Science  9 upvotes 2 years ago
      The conversation discusses the theory that scalp fibrosis contributes to male pattern baldness (MPB) by increasing DHT concentration, and mentions treatments like Minoxidil. The user seeks opinions on the theory and the effectiveness of scalp massages.