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    Glossary WNT genes

    group of genes producing proteins crucial for cell signaling

    WNT genes are a group of genes that produce proteins involved in signaling pathways crucial for cell growth, development, and differentiation. These pathways play a significant role in various biological processes, including embryonic development and the regulation of hair growth, making them important in both normal physiology and diseases like cancer and alopecia.

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    1. Genome-Wide Identification and Characterization of the Wnt Gene Family in Donkey (Equus asinus): Phylogenetic Analysis and Expression Profiling Biology · 2026
    2. The FRZB gene regulates hair follicle development in rabbits via the Wnt/β-catenin signaling pathway World Rabbit Science · 2023
    3. Wnt target gene Ascl4 is dispensable for skin appendage development bioRxiv (Cold Spring Harbor Laboratory) · 2024
    4. The association of Wnt – Factor TCF7L2 (TCF4) gene polymorphism and treated Alopecia Areata (Platelet rich plasma Vs conventional) Zagazig University Medical Journal · 2024
    5. OVO Homolog-Like 1, a Target Gene of the Wnt/β-Catenin Pathway, Controls Hair Follicle Neogenesis Journal of Investigative Dermatology · 2013 · 9 citations
    6. Expression of Wnt Genes in Echinaster Sepositus Arm Regeneration International Journal of Biochemistry & Physiology · 2018 · 2 citations
    7. Competitive balance of intrabulge BMP/Wnt signaling reveals a robust gene network ruling stem cell homeostasis and cyclic activation Proceedings of the National Academy of Sciences · 2013 · 176 citations
    8. Faculty Opinions recommendation of Competitive balance of intrabulge BMP/Wnt signaling reveals a robust gene network ruling stem cell homeostasis and cyclic activation. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2013
    9. Low‐level laser activates Wnt/β‐catenin signaling pathway‐promoting hair follicle stem cell regeneration and wound healing: Upregulate the expression of key downstream gene Lef 1 Skin Research and Technology · 2024 · 2 citations
    10. Suppression of Wnt/β-catenin signaling by EGF receptor is required for hair follicle development Molecular Biology of the Cell · 2018 · 25 citations
    11. Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities Signal Transduction and Targeted Therapy · 2022 · 318 citations
    12. Bioinformatic analysis of gene expression data reveals Src family protein tyrosine kinases as key players in androgenetic alopecia Frontiers in Medicine · 2023
    13. High-Throughput Screening for Discovering Small Molecules Capable of Increasing the Wnt/β-Catenin Signaling Pathway to Promote Hair and Nail Growth Research Square (Research Square) · 2024
    14. Crosstalk between androgen and Wnt/β-catenin leads to changes of wool density in FGF5-knockout sheep Cell Death and Disease · 2020 · 23 citations
    15. CD133-positive dermal papilla-derived Wnt ligands regulate postnatal hair growth Biochemical Journal · 2016 · 15 citations
    16. Roles of <i>jumonji</i> and <i>jumonji</i> family genes in chromatin regulation and development Developmental Dynamics · 2006 · 178 citations
    17. Epithelial Wnt Ligand Secretion Is Required for Adult Hair Follicle Growth and Regeneration Journal of Investigative Dermatology · 2012 · 170 citations
    18. Hairless triggers reactivation of hair growth by promoting Wnt signaling Proceedings of the National Academy of Sciences of the United States of America · 2005 · 137 citations
    19. Tuning Wnt Signals for More or Fewer Hairs Journal of Investigative Dermatology · 2013 · 39 citations
    20. Hairless controls hair fate decision via Wnt/β–catenin signaling Biochemical and Biophysical Research Communications · 2017 · 6 citations
    21. Mutation of the GDP-Fucose Biosynthesis Gene gmds Increases Hair Cell Number and Neuromast Regenerative Capacity in Zebrafish International Journal of Molecular Sciences · 2025 · 1 citations
    22. Revolutionary Approaches to Hair Regrowth: Follicle Neogenesis, Wnt/ß-Catenin Signaling, and Emerging Therapies Cells · 2025
    23. Time-course RNA-seq analysis reveals stage-specific and melatonin-triggered gene expression patterns during the hair follicle growth cycle in Capra hircus BMC Genomics · 2022 · 9 citations
    24. In Ovo Injection of CHIR-99021 Promotes Feather Follicle Development via Modulating the Wnt Signaling Pathway and Transcriptome in Goose Embryos (Anser cygnoides) Frontiers in physiology · 2022 · 6 citations
    25. In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators Nature Cell Biology · 2014 · 173 citations
    26. Comparative Transcriptome Analysis of the Regenerating Zebrafish Telencephalon Unravels a Resource With Key Pathways During Two Early Stages and Activation of Wnt/β-Catenin Signaling at the Early Wound Healing Stage Frontiers in Cell and Developmental Biology · 2020 · 33 citations
    27. Isoxazole 9 (ISX9), a small molecule targeting Axin, activates Wnt/β‐catenin signalling and promotes hair regrowth British Journal of Pharmacology · 2023 · 11 citations
    28. Gene Expression Profiling of the Intact Dermal Sheath Cup of Human Hair Follicles Acta dermato-venereologica · 2018 · 11 citations
    29. miR-200a Targets PITX2 to Mediate Goose Fibroblast Proliferation Through the Wnt Pathway Animals · 2025
    30. Flavonoid Silibinin Increases Hair-Inductive Property Via Akt and Wnt/��-Catenin Signaling Activation in 3-Dimensional-Spheroid Cultured Human Dermal Papilla Cells Journal of Microbiology and Biotechnology · 2019 · 29 citations