Molecular Regulatory Mechanisms in Chicken Feather Follicle Morphogenesis

The review "Molecular Regulatory Mechanisms in Chicken Feather Follicle Morphogenesis" delves into the intricate signaling pathways and genetic elements involved in the development of feather follicles in chickens. Key pathways such as Wnt, Eda, EGF, FGF, BMP, Shh, and Notch are crucial for various stages of feather formation, influencing cell proliferation, differentiation, and migration. The study emphasizes the significant roles of non-coding RNAs, including miRNAs and lncRNAs, in regulating feather growth and morphogenesis. Specific miRNAs like gga-miR-10b-3p and gga-miR-204, and lncRNAs such as lnc5351 and lnc7349, are highlighted for their roles in feather placode development and Wnt signaling pathways. The findings provide a comprehensive understanding of the molecular mechanisms underlying feather development, with potential implications for poultry breeding and biotechnology.