Transcriptional Characteristics Show That miR-144-y/FOXO3 Participates in Embryonic Skin and Feather Follicle Development in Zhedong White Goose

August 2022 in “ Animals ”

Ichraf Mabrouk, Yuxuan Zhou, Sihui Wang, Yupu Song, Xianou Fu, Xiaohui Xu, Tuoya Liu, Yudong Wang, Ziqiang Feng, Jinhong Fu, Jingyun Ma, Fangming Zhuang, Heng Cao, Honglei Jin, Jingbo Wang, Yongfeng Sun

miR-144-y FOXO3 Wnt signaling cell cycle transcriptome next-generation sequencing differentially expressed genes DEGs dual-luciferase reporter assays

Studysummary This study identified key genes and miRNAs involved in feather morphogenesis in Zhedong White geese, highlighting a negative correlation between FOXO3 and miR-144-y.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

View this study on mdpi.com →

Discuss this study in the Community →

Research cited in this study

18 / 18 results

research Expression Profile Analysis of MicroRNAs During Hair Follicle Development in the Sheep Fetus

9 citations , April 2019 in “Bioscience, biotechnology, and biochemistry”

This research identified key miRNAs involved in sheep fetal hair follicle development, highlighting the prolactin signaling pathway and platelet activation as critical processes in secondary follicle initiation.

research Transcriptome Reveals Long Non-Coding RNAs and mRNAs Involved in Primary Wool Follicle Induction in Carpet Sheep Fetal Skin

37 citations , May 2018 in “Frontiers in physiology”

This study identified key long non-coding RNAs and mRNAs involved in primary wool follicle induction in carpet wool sheep, emphasizing their roles in hair follicle development and skin processes.

research Skin Transcriptome Reveals Dynamic Changes in the Wnt Pathway During Integument Morphogenesis of Chick Embryos

23 citations , January 2018 in “PLoS ONE”

In this study, researchers found that changes in Wnt signaling pathways play a crucial role in feather follicle morphogenesis during chicken embryo development.

research Roles of the Hedgehog Signaling Pathway in Epidermal and Hair Follicle Development, Homeostasis, and Cancer

72 citations , November 2017 in “Journal of developmental biology”

This review discusses the role of Hedgehog signaling in epidermal and hair follicle development and its involvement in basal cell carcinoma, without reporting new empirical findings.

research Expression of Fox-Related Genes in the Skin Follicles of Inner Mongolia Cashmere Goat

11 citations , June 2017 in “Asian-Australasian journal of animal sciences”

In this study, researchers found that the FoxN1, FoxE1, and FoxI3 genes are likely involved in hair follicle growth and development in cashmere goat fetuses.

research TGF-β Family Signaling in Epithelial Differentiation and Epithelial-Mesenchymal Transition

82 citations , February 2017 in “Cold Spring Harbor Perspectives in Biology”

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Immunolocalization of a Histidine-Rich Epidermal Differentiation Protein in the Chicken Supports the Hypothesis of an Evolutionary Developmental Link Between the Embryonic Subperiderm and Feather Barbs and Barbules

research Immunolocalization of a Histidine-Rich Epidermal Differentiation Protein in the Chicken Supports the Hypothesis of an Evolutionary Developmental Link Between the Embryonic Subperiderm and Feather Barbs and Barbules

22 citations , December 2016 in “PloS one”

In this study, researchers found that the EDMTFH protein is present in specific layers of the chicken embryo skin and feathers, suggesting its role in feather mechanics and development.

research Epidermal Growth Factor Promotes Proliferation of Dermal Papilla Cells via Notch Signaling Pathway

36 citations , April 2016 in “Biochimie”

This study shows that the concentration of epidermal growth factor (EGF) is crucial for determining whether mink hair follicles are promoted or inhibited in vitro, with involvement of the Notch signaling pathway in DP cell proliferation.

research Comparative Transcriptome Analysis of Fetal Skin Reveals Key Genes Related to Hair Follicle Morphogenesis in Cashmere Goats

127 citations , March 2016 in “PLoS ONE”

This study found that transcriptome profiling of cashmere goat skin revealed key genes and pathways involved in hair follicle initiation, differentiation, and maturation, which are critical for improving fleece production.

research An Integrated Transcriptome Atlas of Embryonic Hair Follicle Progenitors, Their Niche, and the Developing Skin

173 citations , August 2015 in “Developmental cell”

This study characterizes gene expression patterns in embryonic hair follicle progenitors and their niche, identifying signaling pathways like axon guidance that may drive cellular rearrangements for hair follicle formation.

research MicroRNA-214 Controls Skin and Hair Follicle Development by Modulating the Activity of the Wnt Pathway

103 citations , November 2014 in “Journal of Cell Biology”

This study found that overexpression of miR-214 in keratinocytes inhibits hair follicle development and cycling by targeting β-catenin in the Wnt signaling pathway.

research Development, Regeneration, and Evolution of Feathers

151 citations , November 2014 in “Annual Review of Animal Biosciences”

This review discusses three decades of progress in feather development, regeneration, and evolution, with no new experimental results; it highlights feathers' potential as a model for morphogenesis studies.

research Early Inductive Events in Ectodermal Appendage Morphogenesis

160 citations , January 2014 in “Seminars in cell & developmental biology”

This review discusses the shared molecular and cellular processes in the early development stages of skin appendages like hair follicles, teeth, and mammary glands, reporting no new results.

research Transcriptome Sequencing Reveals Differences Between Primary and Secondary Hair Follicle-Derived Dermal Papilla Cells of the Cashmere Goat

81 citations , September 2013 in “PLoS ONE”

This study identified gene expression differences between dermal papilla cells from primary and secondary hair follicles in Cashmere goats, highlighting their roles in hair follicle morphogenesis.

research Wnt Signaling in Skin Development, Homeostasis, and Disease

260 citations , December 2012 in “Cold Spring Harbor Perspectives in Biology”

This review discusses the significant role of Wnt signaling in skin development, homeostasis, and disease, highlighting recent advances in understanding its diverse functions, but reports no new experimental results.

research Mesenchymal–Epithelial Interactions During Hair Follicle Morphogenesis and Cycling

300 citations , August 2012 in “Seminars in Cell & Developmental Biology”

This review discusses mesenchymal–epithelial interactions in hair follicle development and cycling, highlighting recent insights without reporting new experimental results.

research Genetic Basis of Skin Appendage Development

111 citations , January 2007 in “Seminars in cell & developmental biology”

This article reviews the similarities in early development processes of hair follicles, teeth, and mammary glands and reports no new experimental findings.

research Molecular Signaling in Feather Morphogenesis

85 citations , October 2006 in “Current opinion in cell biology”

This article reviews advances in feather development and regeneration, including pattern formation, stem cell biology, and evolution, but presents no new experimental results.