Expression of Fox-Related Genes in the Skin Follicles of Inner Mongolia Cashmere Goat

March 2018 in “ Asian-Australasian journal of animal sciences ”

Wenjing Han, Xiaoyan Li, Xun Hu, Honghao Wang, Kun Yang, Zhixin Wang, Ruijun Wang, Rui Su, Zhihong Liu, Yanhong Zhao, Yanjun Zhang, Jinquan Li

FoxN1 FoxE1 FoxI3 hair follicle development hair follicle differentiation cyclical hair growth

TLDR Fox genes are important for hair growth and development in cashmere goats.

The study investigated the expression of FoxN1, FoxE1, and FoxI3 genes in the skin follicles of Inner Mongolia cashmere goats at various fetal and adult stages. Researchers found that FoxN1 and FoxE1 genes peaked in expression around gestational days 135 and 95, respectively, while FoxI3 peaked earlier at day 75. These genes were also differentially expressed in adult goats, with higher levels of FoxN1 and FoxE1 in September. The findings indicated that these Fox genes play crucial roles in hair follicle development, differentiation, and cyclical growth, providing insights that could improve cashmere production and address hair growth issues in other species.

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