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    GlossaryHair Follicle Differentiation

    process where hair follicle cells become specialized structures

    Hair follicle differentiation is the process by which cells within the hair follicle develop into specialized cell types that form the various structures of the hair, such as the hair shaft, inner root sheath, and outer root sheath. This process is crucial for the growth and maintenance of healthy hair, involving a complex interplay of genetic, molecular, and environmental factors.

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      learn Follistatin

      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

      learn Tretinoin

      the gold standard retinoid in dermatology that's also helpful for hair regrowth alongside Minoxidil

      learn Melatonin

      hormone commonly taken for sleep aid has some topical benefits for hair

      learn Latanoprost

      glaucoma medication with hair follicle stimulant effects

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      community Verteporfin and Microneedling

      in Treatments 3 months ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

      community New and Interesting HairLoss Studies/Papers/Reviews

      in Treatment  42 upvotes 4 years ago
      Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.