Learning From Nudity: Lessons From The Nude Phenotype

    October 2005 in “ Experimental Dermatology ”
    Lars Mecklenburg, Birte Tychsen, Ralf Paus
    Studysummary This review explores the role of Foxn1 in mammalian skin biology, discussing its influence on hair follicle function and the potential for further research to enhance understanding of epithelial differentiation.
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    Research cited in this study 29

    1. Hair Follicle Expression of 1,25-Dihydroxyvitamin D3 Receptors During the Murine Hair Cycle British Journal of Dermatology · 2006
    2. FOXN1 Is Critical for Onycholemmal Terminal Differentiation in Nude (Foxn1nu) Mice ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2004
    3. Penetration Profile of Microspheres in Follicular Targeting of Terminal Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2004
    4. Cyclosporin A: A New Drug in the Field of Canine Dermatology Veterinary Dermatology · 2004
    5. Hair Growth Induction by the Tellurium Immunomodulator AS101: Association with Delayed Terminal Differentiation of Follicular Keratinocytes and Ras-Dependent Up-Regulation of KGF Expression The FASEB Journal · 2003
    6. Cyclosporin A-Induced Hair Growth in Mice Is Associated with Inhibition of Calcineurin-Dependent Activation of NFAT in Follicular Keratinocytes American Journal of Physiology-cell Physiology · 2003
    7. Bone Morphogenetic Proteins and Their Antagonists in Skin and Hair Follicle Biology Journal of Investigative Dermatology · 2003
    8. Cyclic Alopecia in Msx2 Mutants: Defects in Hair Cycling and Hair Shaft Differentiation Development · 2002
    9. Vitamin D3 Analogs Stimulate Hair Growth in Nude Mice Endocrinology · 2002
    10. Targeted Expression of Human Vitamin D Receptor in the Skin Promotes the Initiation of the Postnatal Hair Follicle Cycle and Rescues Alopecia in Vitamin D Receptor Null Mice ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    11. Lack of the Vitamin D Receptor Is Associated with Reduced Epidermal Differentiation and Hair Follicle Growth ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    12. Targeting Expression of the Human Vitamin D Receptor to the Keratinocytes of Vitamin D Receptor Null Mice Prevents Alopecia Endocrinology · 2001
    13. Mutant Laboratory Mice With Abnormalities in Hair Follicle Morphogenesis, Cycling, and Structure: Annotated Tables Experimental dermatology · 2001
    14. The Nude Gene and the Skin Experimental Dermatology · 2001
    15. Cyclosporin A Promotes Hair Epithelial Cell Proliferation and Modulates Protein Kinase C Expression and Translocation in Hair Epithelial Cells Journal of Investigative Dermatology · 2001
    16. Atrichia Caused by Mutations in the Vitamin D Receptor Gene Is a Phenocopy of Generalized Atrichia Caused by Mutations in the Hairless Gene ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2001
    17. Forkhead/Winged-Helix Transcription Factor Whn Regulates Hair Keratin Gene Expression: Molecular Analysis of the Nude Skin Phenotype Developmental Dynamics · 2000
    18. Genetically Separable Determinants of Hair Keratin Gene Expression Developmental Dynamics · 2000
    19. Several Selective Protein Kinase C Inhibitors Including Procyanidins Promote Hair Growth Skin pharmacology and physiology · 2000
    20. Whn and mHa3 Are Components of the Genetic Hierarchy Controlling Hair Follicle Differentiation Mechanisms of Development · 1999
    21. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    22. Ectopic Expression of the Nude Gene Induces Hyperproliferation and Defects in Differentiation: Implications for the Self-Renewal of Cutaneous Epithelia Developmental biology · 1999
    23. Molecular and Functional Aspects of the Hairless (Hr) Gene in Laboratory Rodents and Humans Experimental Dermatology · 1998
    24. Interleukin-1β Is Differentially Expressed by Human Dermal Papilla Cells in Response to PKC Activation and Is a Potent Inhibitor of Human Hair Follicle Growth in Organ Culture Journal of interferon & cytokine research · 1997
    25. Bisindolylmaleimide Protein Kinase C Inhibitors Delay the Decline in DNA Synthesis in Mouse Hair Follicle Organ Cultures Skin Pharmacology and Physiology · 1997
    26. An Update of Hair Shaft Disorders Dermatologic clinics · 1996
    27. Hair Keratinization in Health and Disease Dermatologic clinics · 1996
    28. Effect of Cyclosporin on Hair-Existing Area of Nude Mice Journal of Dermatological Science · 1994
    29. Hair Growth on Nude Mice Due to Cyclosporin A The Journal of Dermatology · 1991

    Related research 4

    1. Mutant Laboratory Mice With Abnormalities in Hair Follicle Morphogenesis, Cycling, and Structure: An Update Journal of Dermatological Science · 2012
    2. Hairless Plays a Role in Formation of Inner Root Sheath via Regulation of Dlx3 Gene Journal of biological chemistry/˜The œJournal of biological chemistry · 2012
    3. Electron Paramagnetic Resonance Spectroscopy for Investigating Murine Telogen Skin After Spontaneous or Depilation-Induced Hair Growth Journal of Dermatological Science · 2008
    4. Towards a Molecular Understanding of Hair Loss and Its Treatment Trends in Molecular Medicine · 2001