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research Hair Cycle Resting Phase Is Regulated by Cyclic Epithelial FGF18 Signaling

158 citations , February 2012 in “Journal of Investigative Dermatology”

FGF18 helps keep hair in its resting phase, affecting hair growth cycles.

research Cells within the bulge region of mouse hair follicle transiently proliferate during early anagen: heterogeneity and functional differences of various hair cycles

130 citations , January 1994 in “Differentiation”

In this study, researchers found that bulge cells in mouse hair follicles undergo transient proliferation during early anagen, indicating their role as follicular stem cells. However, another factor beyond dermal papilla proximity may be required to initiate a new anagen phase.

research Complex Hair Cycle Domain Patterns and Regenerative Hair Waves in Living Rodents

127 citations , December 2007 in “Journal of Investigative Dermatology”

This review examines regenerative hair waves and complex hair cycle domains in transgenic mice, highlighting how these dynamic processes contribute to skin regeneration and the physiological regulation of organs, but reports no new experimental results.

research A Meeting of Two Chronobiological Systems: Circadian Proteins Period1 and BMAL1 Modulate the Human Hair Cycle Clock

92 citations , September 2013 in “Journal of Investigative Dermatology”

This study found that peripheral clock genes, particularly BMAL1 and Period1, modulate human hair follicle cycling, suggesting their potential as therapeutic targets for affecting hair growth.

research Hair Cycle Control by Estrogens: Catagen Induction via Estrogen Receptor (ER)-α Is Checked by ERβ Signaling

92 citations , February 2005 in “Endocrinology”

This study found that estrogen receptor beta plays a significant role in murine hair growth control, potentially acting as a silencer of estrogen receptor alpha's catagen-promoting effects.

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community if hair follicle miniaturization happens slowly and gradually over a few hair cycles then wouldn't that mean that to regain maximum or top thickness from treatment you would at least need 5-10 years?

in Research/Science 53 upvotes 10 months ago

Hair regrowth from treatments like finasteride, dutasteride, and minoxidil can take several years, with most visible results appearing within 1-2 years and potential improvements continuing up to 10 years. Consistency and patience are crucial for achieving maximum hair thickness, as hair miniaturization and regrowth are gradual processes.

community My hair after 3 steroid cycles

in Progress Pictures 27 upvotes 2 years ago

A user shared their hair progress after three steroid cycles, using 5% minoxidil and 100mg RU58841 daily. They are considering a hair transplant due to paranoia about shedding.

community Cycle of Hair Loss: Fin to Dut Transition without Improvement

in Basic Questions 129 upvotes 5 months ago

The user has been experiencing worsening hair loss despite using finasteride, minoxidil, and later switching to dutasteride. Despite normal bloodwork and consulting dermatologists, the hair loss continues without improvement.

community True hair loss Vs shedding cycle

2 upvotes 7 months ago

The user stabilized hair loss with oral finasteride, dutasteride, and topical minoxidil, and underwent a stem cell and PRP procedure. Recent increased hair shedding may be due to restarting dermarolling, affecting minoxidil absorption, or the waning effects of the stem cell treatment.

community Help me understand hair/shed cycles. After 6 months of Fin, losing ground again

15 upvotes 4 years ago

After 6 months of using finasteride, minoxidil, RU58841, and microneedling, the user experienced hair regrowth but then noticed a significant shed, returning to the initial state of hair loss. Another user responded that shedding every 6-8 months is normal when using finasteride and advised to continue the treatment for thicker hair regrowth.

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Learn

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learn Hair Transplant

What happens after a hair transplant? Expect mild swelling and redness, with new hair growth starting in 3 to 6 months.
When will I see new hair growth after a hair transplant? New hair growth usually starts 2-4 months after a hair transplant.

learn Vitis vinifera

Does Vitis vinifera help protect hair follicles from damage? Grape compounds show antioxidant activity in lab studies and affected the hair cycle in mice; no study, in animals or people, shows they protect hair follicles.
What is Vitis vinifera, and does it benefit hair health? Grape (Vitis vinifera) extracts show antioxidant activity in lab studies and affected the hair cycle in mice, but no human trial shows they help hair growth.

learn Cyproterone

How long does it take for cyproterone to work on hair loss? There is no reliable published figure for how fast cyproterone works on hair loss: the hair cycle means nothing shows for months, the one randomised trial assessed women at twelve months, and community reports range from about six months to two years — with some people seeing no change at all.