Molecular and Functional Aspects of the Hairless (Hr) Gene in Laboratory Rodents and Humans

    October 1998 in “ Experimental Dermatology ”
    Andrey A. Panteleyev, Ralf Paus, Wasim Ahmad … Angela M. Christiano
    Studysummary This review provides an overview of the hairless gene in mice and humans, discussing its structure, expression, and implications for understanding skin physiology and human disorders related to gene disruption, but it reports no new empirical findings.
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    Research cited in this study 18

    1. A Missense Mutation in the Zinc-Finger Domain of the Human Hairless Gene Underlies Congenital Atrichia in a Family of Irish Travellers The American Journal of Human Genetics · 1998
    2. Towards Defining the Pathogenesis of the Hairless Phenotype Journal of Investigative Dermatology · 1998
    3. Pathobiology of the Hairless Phenotype: Dysregulation of Hair Follicle Apoptosis and Topobiology During the Initiation of Follicle Cycling Journal of Dermatological Science · 1998
    4. Alopecia Universalis Associated With a Mutation in the Human Hairless Gene Science · 1998
    5. Transforming Growth Factor-β Receptor Type I and Type II Expression During Murine Hair Follicle Development and Cycling Journal of Investigative Dermatology · 1997
    6. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) Affects Keratin 1 and Keratin 17 Gene Expression and Differentially Induces Keratinization in Hairless Mouse Skin Journal of Investigative Dermatology · 1997
    7. Keratin 17 Gene Expression During the Murine Hair Cycle Journal of Investigative Dermatology · 1997
    8. Modulation of Murine Hair Follicle Function by Alterations in Ornithine Decarboxylase Activity Journal of Investigative Dermatology · 1996
    9. Dynamic Expression Patterns of Tenascin, Proteoglycans, and Cell Adhesion Molecules During Human Hair Follicle Morphogenesis Developmental dynamics · 1994
    10. Insertional Mutation of the Hairless Locus on Mouse Chromosome 14 Mammalian Genome · 1993
    11. Atrichia and Papular Lesions: Report of a Case Dermatology · 1992
    12. Adhesion Molecules in Skin Development: Morphogenesis of Feather and Hair Annals of the New York Academy of Sciences · 1991
    13. Meibomian Gland Changes in the Rhino Mouse PubMed · 1988
    14. Atrichia With Papular Lesions Archives of Dermatology · 1986
    15. Outer Root Sheath Keratinization in Anagen and Catagen of the Mammalian Hair Follicle: A Seventh Distinct Type of Keratinization in the Hair Follicle - Trichilemmal Keratinization PubMed · 1981
    16. Growth of the Hair Physiological Reviews · 1954
    17. The Expression And Interaction Of Hereditary Factors Producing Hypotrichosis In The Mouse: Histology And Experimental Results Canadian Journal of Research/Canadian journal of research · 1946
    18. The Character 'Hairless' in the Mouse Journal of Genetics · 1931