Search

for
Search:

Did you mean Mutation?

Glossary Mutation

A mutation is a change in the DNA sequence of an organism that can lead to alterations in gene function and expression. In the context of hair loss, certain mutations can affect the genes responsible for hair follicle development, growth cycles, and overall hair health, potentially leading to conditions such as androgenetic alopecia or alopecia areata. Key distinguishing characteristics of mutations include their ability to be inherited or acquired, and their potential to either have no effect, be beneficial, or cause detrimental changes in hair biology.

Related Terms

Research

5 / 1000+ results

research Mutations in the hair cortex keratin hHb6 cause the inherited hair disease monilethrix

175 citations , August 1997 in “Nature Genetics”

research Cantú Syndrome Is Caused by Mutations in ABCC9

148 citations , May 2012 in “The American Journal of Human Genetics”

This study identified heterozygous mutations in the ABCC9 gene as the genetic basis of Cantú syndrome, suggesting the syndrome as a new member of potassium channelopathies.

research Mutations in Three Genes Encoding Proteins Involved in Hair Shaft Formation Cause Uncombable Hair Syndrome

119 citations , November 2016 in “American journal of human genetics”

This study reports the discovery of mutations in the PADI3, TGM3, and TCHH genes as molecular genetic causes of uncombable hair syndrome in children, indicating an autosomal-recessive inheritance pattern.

research Mutations in the vitamin D receptor and hereditary vitamin D-resistant rickets

107 citations , March 2014 in “BoneKEy Reports”

This abstract reviews hereditary vitamin D-resistant rickets, a rare genetic condition causing severe early childhood rickets, and reports no new results; effective treatment typically requires high doses of calcium to address hypocalcemia and secondary hyperparathyroidism.

research Mutations in ABCB6 Cause Dyschromatosis Universalis Hereditaria

99 citations , March 2013 in “Journal of Investigative Dermatology”

This study identified ABCB6 as the first gene linked to dyschromatosis universalis hereditaria (DUH) in a large Chinese family, suggesting it plays a role in skin pigmentation.

View more "mutations" in research →

Learn

— no results

Try a deeper search in learn →

Community Join

— no results

Try a deeper search in community →

Experts

— no results

Try a deeper search in experts →

Clinics

— no results

Try a deeper search in clinics →