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GlossaryBRAF Mutation

mutation in the BRAF gene affects cell growth and division

A BRAF mutation refers to a change in the BRAF gene, which plays a crucial role in cell growth and division. This mutation can lead to uncontrolled cell proliferation and is often associated with various cancers, including melanoma, colorectal cancer, and thyroid cancer. The most common BRAF mutation is V600E, where valine (V) is replaced by glutamic acid (E) at position 600 in the protein. This mutation can be a target for specific cancer therapies, making it a significant focus in oncology.

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Lentiginous Melanoma: A Clinically Malignant Entity That Histopathologically Seems Benign. Case Study Harboring BRAF V600R Mutation

research Lentiginous Melanoma: A Clinically Malignant Entity That Histopathologically Seems Benign. Case Study Harboring BRAF V600R Mutation

1 citations , March 2015 in “Journal of the European Academy of Dermatology and Venereology”

A clinically suspected melanoma appeared benign under the microscope but was confirmed by specific tests and a rare mutation.

research Diagnosis and Management of Melanoma of the Scalp: A Review of the Literature

3 citations , October 2021 in “Clinical, Cosmetic and Investigational Dermatology”

Scalp melanoma, a deadly skin cancer, is often found late due to its hard-to-see location, especially in older men. Early detection, possible treatments, and the role of hairdressers in spotting it early are discussed. More research is needed to improve detection and treatment.

research Author Response: Dynamics of Nevus Development Implicate Cell Cooperation in the Growth Arrest of Transformed Melanocytes

September 2020

Moles may stop growing because of cell cooperation, not just because of aging cells.

research Hair Matters in Melanoma Biology

7 citations , May 2020 in “Trends in molecular medicine”

The document concludes that the immune-inhibitory environment of the hair follicle may prevent melanoma development.

research Dyad of Infantile Cutaneous and Thymic Langerhans Cell Histiocytosis: Is It Rare?

October 2023 in “Pediatric blood & cancer”

Thymic LCH may be underdiagnosed, so thymic ultrasound should be considered in infants with cutaneous LCH.

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community Huge Group Buy is Now Live with New and Existing Treatments

in Product 146 upvotes 2 years ago

A group buy for hair loss treatments including Harmine 19a, TM5614, Abiraterone Acetate, and others. A compound, BMS-202, that can potentially reverse gray hair is also mentioned.