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    Glossary RAF inhibitors

    block proteins involved in cell growth signaling pathways

    RAF inhibitors, also known as RAF kinase inhibitors, are a class of drugs designed to block the activity of RAF kinases, which are proteins involved in cell signaling pathways that control cell growth and division. These inhibitors are particularly important in the treatment of certain cancers, such as melanoma, where mutations in the RAF gene (e.g., BRAF mutations) lead to uncontrolled cell proliferation. By inhibiting RAF kinases, these drugs can help to slow down or stop the growth of cancer cells.

    Research 10 of 376

    1. Abstract 1677: Epithelial hyperplasia induced by a selective B-Raf inhibitor, WYE-130600 Cancer Research · 2010 · 1 citations
    2. The incidence and management of cutaneous adverse events of the epidermal growth factor receptor inhibitors Postępy Dermatologii i Alergologii · 2017 · 18 citations
    3. Dermatologic Side Effects of Systemic Targeted Anticancer Therapy Springer eBooks · 2018
    4. Sorafenib-induced eruption resembling pityriasis rubra pilaris Journal of the American Academy of Dermatology · 2011 · 21 citations
    5. Cutaneous adverse effects of targeted therapies Journal of the American Academy of Dermatology · 2015 · 149 citations
    6. 329 Mechanisms of Cutaneous Adverse Events during Targeted Cancer Therapy 2022
    7. Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARα and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways Journal of Cellular Biochemistry · 2005 · 24 citations
    8. Self‐Assembled Peptide Hydrogels Loaded with Umbilical Cord‐Derived Mesenchymal Stem Cells Repairing Injured Endometrium and Restoring Fertility Advanced Healthcare Materials · 2024 · 11 citations
    9. Biological therapy in the treatment of melanoma Journal of Mind and Medical Sciences · 2018 · 3 citations
    10. From bench to babies – drug development for male subfertility Reproduction and Fertility · 2024
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