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research Genetic alteration of cyclic adenosine 3',5'-monophosphate-dependent protein kinase subunit expression affects calcium currents and beta-endorphin release in AtT-20 clonal pituitary cells.
This study found that AtT-20 pituitary cells with higher cAMP-dependent kinase activity had larger calcium currents and significantly increased beta-endorphin release compared to cells with lower kinase activity.
research Heterogeneity in the genetic alterations and in the clinical presentation of acrodermatitis enteropathic: Case report and review of the literature
A novel mutation in the SLC39A4 gene was identified in an infant with mild, incomplete acrodermatitis enteropathic symptoms, suggesting genetic testing is beneficial even without the full symptom triad.
research Is knowledge about the genetic and epigenetic alterations in melanoma a basis for targeted therapy?
This review discusses the genetic pathways involved in melanoma and suggests that targeting these pathways with pharmacological inhibitors may provide a new therapeutic approach, though clinical results have been disappointing so far.
research Skin and hair abnormalities of Cantu syndrome: A congenital hypertrichosis due to a genetic alteration mimicking the pharmacological effect of minoxidil
This study described specific skin and hair follicle abnormalities in three Japanese patients with Cantu syndrome, which may relate to the regulation role of SUR2 in hair follicle growth.
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5 / 1000+ resultscommunity CRISPR Is Curing People Right Now. Genetic Hair Loss is Next?
CRISPR shows promise for treating hair loss by targeting specific genes. Current treatments include Minoxidil and finasteride, but CRISPR could offer a more precise solution, though it is still expensive and in early stages.
community Justin Trudeau really is one lucky guy
Justin Trudeau's full head of hair at 53 is humorously attributed to unpredictable genetics and possible use of finasteride. The conversation jokes about a resemblance to Fidel Castro, suggesting genetic luck or treatment use.
community If we can clone a sheep why we can't cure baldness till now
Hair loss treatments like Minoxidil, finasteride, and stem cell therapies exist, but a complete cure is hindered by genetic complexity and market dynamics. Cloning hair follicles is considered a potential solution, but it's currently not feasible.
community DHT Harms Scalp Microbiome: DHT Itch is REAL
Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.
community Almost 9 months on only finasteride. 18M. Is this progress?
An 18-year-old is using finasteride for hair loss prevention despite having a healthy hairline. Opinions are mixed, with some advising against its use at his age and others supporting his proactive approach.
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2 / 801 results- Thinning hair over time? It might not just be genetics: lack of B1 and B2 could be silently working against you. There is no verified human trial showing that B1 or B2 deficiency causes thinning hair or that correcting it regrows hair; a 2019 review concludes the role of micronutrients in hair loss is real but unclear and still needs controlled trials.
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