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    GlossaryGenetic Disorders

    conditions caused by DNA abnormalities, often inherited from parents

    Genetic disorders, also known as hereditary disorders or genetic diseases, are conditions caused by abnormalities in an individual's DNA. These abnormalities can be due to mutations in a single gene, multiple genes, or chromosomal changes, and they can be inherited from one or both parents. Examples include cystic fibrosis, sickle cell anemia, and Down syndrome.

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      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp

      learn SCUBE3

      a signaling molecule from dermal papilla cells being actively researched

      learn Dutasteride

      Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity

    Research

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      research Genetic Disorders and Defects in Vitamin D Action

      151 citations, June 2010 in “Endocrinology and metabolism clinics of North America”
      Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.
      Genetic Hair Disorders: A Review

      research Genetic Hair Disorders: A Review

      26 citations, July 2019 in “Dermatology and Therapy”
      The conclusion is that genetic testing is important for diagnosing and treating various genetic hair disorders.

      research Genetic Hair and Nail Disorders

      37 citations, January 2005 in “Clinics in dermatology”
      Recent progress has been made in understanding inherited hair and nail disorders.

    Community Join

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      community CRISPR treatment for AGA on the horizon after approval for blood disorders

      in Treatment  11 upvotes 11 months ago
      CRISPR treatments for blood disorders have been approved, leading to discussions about its potential for treating hair loss (AGA). A study showed that editing a gene related to DHT sensitivity could lead to hair regrowth, suggesting CRISPR may eventually be used for AGA, but it's expected to be expensive and not soon available.

      community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

      in Research/Science  62 upvotes 1 year ago
      Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.