Genetic Hair Disorders: A Review

July 2019 in “ Dermatology and Therapy ”

Azhar Ahmed, Hind M. Almohanna, Jacob Griggs, Antonella Tosti

androgenetic alopecia alopecia areata monilethrix hypotrichosis hair shaft disorders ectodermal dysplasia genetic testing topical minoxidil systemic retinoid therapy Rogaine

TLDR The conclusion is that genetic testing is important for diagnosing and treating various genetic hair disorders.

The document "Genetic Hair Disorders: A Review" from July 22, 2019, provided a comprehensive review of various genetic hair disorders, their causes, symptoms, and potential treatments. The disorders discussed included androgenetic alopecia, alopecia areata, monilethrix, hypotrichosis, hair shaft disorders, and ectodermal dysplasia, among others. These disorders were often caused by mutations in specific genes, which could be inherited from one or both parents. The review emphasized the importance of genetic testing in diagnosing these conditions and guiding treatment strategies. Treatments varied from disorder to disorder, with some showing promising results with topical minoxidil and systemic retinoid therapy, while others had no cure and treatment focused on managing symptoms. The document was based on a review of 159 articles published within the last 50 years.

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35 / 35 results

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36 citations , October 2018 in “Dermatologic Clinics”

Trichoscopy is a useful tool for diagnosing hair disorders without pulling out hair.

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A new mutation in the CDH3 gene causes hair loss and vision problems in a young girl.

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A 6-year-old girl was diagnosed with a rare hair disorder and started treatment with topical minoxidil.

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A new genetic mutation in the CDH3 gene causes hair loss and eye problems in young people.

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Oral etretinate improved hair length and reduced beading in monilethrix.

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28 citations , January 1985 in “Journal of the American Academy of Dermatology”

A girl with citrullinemia developed pili torti, suggesting a link between the hair condition and the metabolic disorder.

5 / 5 results

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Many hair loss conditions can be treated.